Aneurysmal bone cysts are infrequent in the craniofacial region. These cysts are non-neoplastic, expansile, and osteolytic in nature. Since these cysts are not lined by epithelium, they are considered as pseudocysts. Clinicopathological features and biological behavior of these cysts are enigmatic as they mimic various other pathogenetic lesions and two third of these cysts are associated with other bone pathology. Aim of the present paper was to report a case of aneurysmal bone cyst in 40-year-old female patient encountered in left mandibular posterior region which was surgically treated with hemimandibulectomy. The post-operative period was uneventful. Furthermore, emphasis was given to discuss its etiopathogenesis, clinicopathological variants, and other pathologies associated with this cyst.
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