A rapid, solvent free synthetic strategy for the oxidative cyclocondensation of 2-aminobenzenethiols and 1,3-dicarbonyls using a catalytic amount of hydrazine hydrate has been developed in order to obtain 2,3-disubstituted-1,4-benzothiazines in high yields (83-96%).
Rapid, quantitative and regioselective O-acylation/O-benzoylation of hydroxamic acids has been carried using polymer supported hydroxamate anions and acetyl/benzoyl chloride under mild conditions. The isolation of unambiguous and pure products by simple work-up is also an important feature of this method.
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