As mortality due to AIDS-related causes has decreased with the use of antiretroviral therapy, there has been a rise in deaths related to non-AIDS-defining illnesses. Given the exceedingly high prevalence of cigarette smoking among individuals living with HIV infection, tobacco has been implicated as a major contributor to this paradigm shift. Evidence suggests that smoking-related illnesses, such as cardiovascular disease, respiratory illnesses, and certain malignancies, contribute substantially to morbidity and mortality among HIV-infected persons. In this review, we summarize the adverse health consequences of smoking relevant to HIV-infected individuals and discuss smoking cessation in this unique population, including a discussion of barriers to quitting and a review of studies that have examined smoking cessation interventions.
The prevalence of tobacco use in women has increased over the past century. This has resulted in dramatic increases in smoking-related lung diseases, such as chronic obstructive pulmonary disease (COPD) and lung cancer. There is growing literature suggesting that women may be more susceptible than men to the effects of tobacco and to the development of COPD. Women may also have specific barriers that interfere with smoking cessation. This article addresses possible differences in lung function decline and nicotine metabolism in women compared to men. Differences in COPD between the sexes are discussed. Finally, barriers to smoking cessation in women are presented.
Introduction:One of the basic needs of human is sleep. Research has shown that poor quality of sleep is the 3rd problem in the elderly people, being one of their most common complaints and reason to refer to doctors. The objective of this survey is to study the frequency of sleep disorder and how to deal with it. Materials and Methods:This cross-sectional study was conducted on 360 people aged 60 or older, using a self-made structured questionnaire and interview. The data entered into SPSS, version 11.5. Descriptive and analytical statistics such as Chi square and Fisher exact tests were used to analyze the data. Results:In this survey, the mean age of the subjects was 67.7±7.33; 70.3% suffered sleep disorder and 81.81% of them had primary insomnia. Sleep disorder showed a significant relationship whit marital status, gender, residency, education and employment. In this survey, 94.5% (239 men) that had sleep disorder used at least one of the non-pharmacological methods and7.5 percent of them used pharmacological methods to cope with sleep disorders. Conclusion:Considering the fact that most of the elderly people used one of the non-pharmacological methods to cope with sleep disorders but still the prevalence of sleep disorders is high, we can conclude that it can be the result of their inappropriate use. Therefore, we recommend that the health care staff should focus on educating the elderly people on how to use the nonpharmacological methods.
Background. HIV-infected subjects have an increased incidence of pulmonary emphysema. There are known gender differences in COPD phenotypic expression and diagnosis, but this is not well characterized in lung disease related to HIV. We analyzed a group at risk for the development of COPD (HIV-infected smokers) to determine gender differences in pulmonary symptoms, pulmonary function tests, and HRCT appearances. Methods. This was a cross-sectional, baseline analysis of a prospective study performed between 2006 and 2010. We performed symptomatic, pulmonary function, and computed tomography assessments in 243 HIV-infected smokers. In a subset bronchoalveolar lavage was performed with proteomic analysis of their alveolar macrophages. Results. The majority of the participants were male 213 (87.6%). There was significantly higher percentage of cough and phlegm production in males. There was also a lower FEV1 and a higher RV in males than females. Proteomic analysis revealed 29 proteins with at least a 2-fold higher expression in males and 13 identified proteins that were higher in females. Conclusions. In this group of HIV-infected smokers, airway symptoms and pulmonary function test abnormalities were higher in men than women. These gender differences may be due to differential expression of certain proteins in this group.
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