Objectives: To assess the maternal and fetal outcomes using new screening criteria with upper serum thyroid stimulating hormone (TSH) cut off as >3mIU/L, for diagnosing hypothyroidism in pregnancy. Materials and Methods: This study was a cross sectional study, carried out in the department of Obstetrics and Gynaecology. During one year of study period from February 2016 to January 2017, pregnant women with ≤ 20 weeks gestation, attending antenatal OPD were included in the study and they were followed till delivery. On the basis of serum TSH level, women were divided into study group with serum TSH level between 3.1 to 6 mIU/L, (new range to be studied) and an equal number of ages and parity matched control group with serum TSH levels between 0.4 to 3 mIU/L. The maternal and fetal outcomes were compared between study and control groups. Results: During the study period, in study group 96 women had serum TSH between 3.1-6 mIU/L. Maternal and fetal outcomes in both the groups were comparable. Study did not find any difference in the rate of spontaneous abortion between women in study and control group [p > 0.99]. There was no significant difference in the maternal complications like preeclampsia, gestational diabetes and placental abruption in the study and control group. Vaginal delivery and caesarean section were similar in both the groups. Study shows no significant difference of foetal outcome in study and control group [p > 0.05]. Conclusion: As compared to pregnant women with serum TSH levels <3mIU/L, women with serum TSH levels between 3.1-6.0mIU/L had no significant adverse fetomaternal outcome.
Objectives: The aim of the study was to evaluate the effects of oligohydramnios on maternal and fetal outcome at term pregnancy. Methodology: A case control study on pregnancy outcome in 100 women with AFI<5cm after 37 completed weeks of pregnancy compared with 100 controls with no oligohydramnios with matched age and parity. Results: Non stress test (NST) was non-reactive in 38% of oligohydramnios and 20% of controls and was statistically significant (P<0.05). Ominous fetal heart patterns were seen in 60% of oligohydramnios and 30% of controls but it was statistically not significant. Thick meconium stained amniotic fluid was seen in 48% of oligohydramnios and 20% of the controls and was significant (P<0.001). In oligohydramnios, 54% were induced whereas in controls, only 24% and was significant (P<0.002). For fetal distress, 88% of oligohydramnios and 90% of controls underwent LSCS and was not significant. APGAR score <7 was insignificant between the two groups. LBW and NICU admission were more in oligohydramnios and was significant (P<0.05, <0.01). Perinatal mortality was not significant between the two groups. Conclusion: Oligohydramnios (AFI<5) is valuable for predicting fetal distress in labour requiring caesarean section, used as an adjunct to other fetal surveillance methods. Oligohydramnios (AFI < 5cm) detected after 37 weeks of gestation is an indicator of poor pregnancy outcome.
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