Background: There is a widespread range of diverse typical and atypical manifestations of malaria. The diagnosis of malaria may escape the attention of treating physician due to its unusual and vague presentations.The morbidity and mortality due to malaria is increased due to lack of early diagnosis and right treatment. The Aim of the present study was to examine the changing clinical pattern of malaria with special attention to atypical presentations.Methods: The present study comprised of 630 cases of definitively diagnosed malaria.Diagnostic methods used were conventional thick and thin peripheral smear stained with Leishman stain and rapid malarial antigen test.Results: This study revealed atypical symptoms like lack of taste (1.3%), throat discomfort (13.33%) and cough (24.0%) and vomiting (52.4%) as presenting complaints. These were significantly more in patients with P. vivax infestations.Conclusions: A high degree of suspicion is necessary for early detection and treatment of malaria, especially of unusual presentations.
Background: Malaria, despite intensive efforts to control, remains a leading cause of morbidity and mortality in humans. India contributes to 61 per cent of malaria cases and 41 per cent of malaria deaths in SEAR countries. The objective of the present study was to find out an incidence of mortality due to malaria with typical and atypical presentation.Methods: The present was conducted over a period of three years. During the study period 630 patients with clinical suspicion of malaria were tested for malaria using peripheral smear, QBC and RDT.Results: The mortality rate in this study group 161 (25.55%) out of which maximum mortality observed in patients with falciparum malaria either singly or with mixed infestation. There is no significant correlation between the typical and atypical presentations in the different age groups with mortality.Conclusions: For timely diagnosis and treatment a high index of suspicion for the disease should be maintained by treating physicians, especially in endemic areas. They should be aware of the varied manifestations to minimize the mortality due to malaria.
16 year old male was operated upon for trauma induced L1 burst fracture with complete paraplegia. On 7 th postoperative day patient started developing rapidly evolving bilaterally symmetrical ascending areflexic motor paralysis involving shoulder accompanied by tingling dysesthesias in the upper extremities. Thereafter, he developed lower cranial nerve palsy with facial diaparesis. All relevant haematological & serological tests were not contributory to definite diagnosis and MRI-Spine did not show any abnormality. However, Electrodiagnostic study & CSF examination supported the diagnosis of Guillain-Barre Syndrome (GBS). Patient was subsequently subjected to plasmapheresis but his condition deteriorated and he succumbed to death on 15 th postoperative day.This rare case reports illustrates the importance of watchful expectancy for a neurodeficit that may or may not be related to spine surgery even after critical postoperative period, so that urgent measures can be initiated at the right time in the form of supportive & curative treatment.
Background: Snake-bite is one of the most life-threatening bio-weapon system in the nature which may cause local to systemic complication. Aim: To analyse the outcome of AKI after snake-bite. Material and Methods: A total of 200 patients of either gender with age >12 years having history of snake bite with signs of envenomation were investigated and treated in a tertiary care hospital. Outcome was analysed. Results: Anti-snake venom was given to all cases in the study. Antibiotics, fresh frozen plasma, whole blood and platelets was given to 48%, 19%, 9% and 7.5% cases respectively. Mortality rate among snake bite cases in present study was reported as 2%. and due to snake bite induced AKI was 19%. Conclusion: Mortality rate among snake bite cases was reported as 2% and due to snake bite induced AKI was 19%. Lapse of time in presenting to the hospital is the predictors of poor outcome in snake bite induced acute kidney injury. Early ASV administration and proper supportive management after ASV administration is of utmost importance, for a good patient outcome.
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