though it is not recommended for use in paediatric populations. For submission of CUAs to Health Technology Appraisal bodies like NICE, utility values derived from clinical trials is preferred over values obtained from literature as commented by ERG in one of the submissions. Mapping data to EQ-5D from a non-preference based measure using data collected from patients experiencing the treatment of interest is accepted as an alternative within the NICE reference case. ConClusions: In the absence of direct utility data from trials, mapping data from other measures to EQ-5D for obtaining utilities for CUA may be an appropriate methodology particularly for paediatric indications.
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