Shinji Funayama scite author profile

The leaves and roots of Rhazya stricta (Apocynaceae) yielded four indole alkaloids. Three of these isolated, vallesiachotamine (1), sewarine (3) and tetrahydrosecamine (4), displayed cytotoxic activity; polyneuridine (2) was not reported previously from this species. Tetrahydrosecaminediol (5), its acetate 6, and didemethoxycarbonyl-tetrahydrosecamine (7) were prepared from tetrahydrosecamine (4) by chemical reactions. The diol 5 was highly cytotoxic.

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Chemistry of Acronycine, II. Dimerization of Noracronycine

Funayama¹,

Cordell²,

Wagner³

et al. 1984

J. Nat. Prod.

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Casein kinase II(CK-II)-Mediated Stimulation of HIV-1 Reverse Transcriptase Activity and Characterization of Selective Inhibitors in Vitro.

Harada

Haneda

Maekawa

et al. 1999

Biological & Pharmaceutical Bulletin

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Kukoamine B, a spermine alkaloid from Lycium chinense

1995

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Shinji Funayama

Structure of kukoamine A, a hypotensive principle of Lycium chinense root barks1

Anticancer Indole Alkaloids of Rhazya stricta

Chemistry of Acronycine, II. Dimerization of Noracronycine

Casein kinase II(CK-II)-Mediated Stimulation of HIV-1 Reverse Transcriptase Activity and Characterization of Selective Inhibitors in Vitro.

Kukoamine B, a spermine alkaloid from Lycium chinense

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