Objectives: In this study we aimed to evaluate diagnostic accuracy of magnetic resonance imaging (MRI) and transvaginal sonography (TVS) in identifying the depth of myometrial invasion and cervical involvement and also their relationship with the uterine arteries resistance index (RI) and pulsatility index (PI) in endometrial carcinoma. Materials and Methods: We performed a prospective study on 45 women with histologically confirmed diagnosis of endometrial carcinoma. The study was performed from October 2009 to December 2012. All the patients were evaluated by 3T MRI and TVS and transvaginal color Doppler sonography of uterine arteries. All the patients underwent hysterectomy and the result of imaging and pathologic studies were compared. Results: Mean age was 54.5 ± 10.8 years (33 to 77 years), mean gravid was 3.93 ± 2.8 and the mean parity was 3.9 ± 2.5. The pathology results indicated 29 patients (64.4%) in stage IA and 16 patients (35.6%) in stage IB. Mean endometrial thickness in stage IA patients was 18.4±14.4 mm and in stage IB patients was 38.5±11.5 mm. TVS also showed positive predictive value (PPV) of 76.5%, negative predictive value (NPV) of 88.9%, sensitivity of 81.3%, specificity of 85.7%, and accuracy of 84.1% for assessment of the depth of myometrial invasion in endometrial carcinoma. We found PPV of 86.7%, NPV of 92.3%, sensitivity of 86.7%, specificity of 92.3%, and accuracy of 90.2% for MRI study. Conclusions: TVS can evaluate the depth of myometrial invasion with an acceptable accuracy when MRI is not available or costeffective, or when MRI is contraindicated. Both preoperative MRI and TVS can predict low risk patients (less than 50% of myometrial invasion) accurately; thereby avoiding lymphadenectomy in these patients.

The outbreak of coronavirus disease 2019 (COVID-19) in late 2019 rapidly turned into a global pandemic. Although the symptoms of COVID-19 are mainly respiratory ones, the infection is associated with a wide range of clinical signs and symptoms. The main imaging modality in COVID-19 is lung computed tomography (CT) scanning, but the diagnosis of the vast spectrum of complications needs the application of various imaging modalities. Owing to the novelty of the disease and its presentations, its complications—particularly uncommon ones—can be easily missed. In this study, we describe some uncommon presentations of COVID-19 diagnosed by various imaging modalities. The first case presented herein was a man with respiratory distress, who transpired to suffer from pneumothorax and pneumomediastinum in addition to the usual pneumonia of COVID-19. The second patient was a hospitalized COVID-19 case, whose clinical condition suddenly deteriorated with the development of abdominal symptoms diagnosed as mesenteric ischemia by abdominal CT angiography. The third patient was a case of cardiac involvement in the COVID-19 course, detected as myocarditis by cardiac magnetic resonance imaging (MRI). The fourth and fifth cases were COVID-19-associated encephalitis whose diagnoses were established by brain MRI. COVID-19 is a multisystem disorder with a wide range of complications such as pneumothorax, pneumomediastinum, mesenteric ischemia, myocarditis, and encephalitis. Prompt diagnosis with appropriate imaging modalities can lead to adequate treatment and better survival.

Breast cancer is the second most common cause of cancer-related mortality in women worldwide, with a lifetime risk of approximately 12% (1). Tumor size is one of the main prognostic factors in breast cancer and is reported to correlate with lymph node involvement, tumor grade, and overall survival rate (2). Tumor size is also a factor assessed to determine treatment plans: breast conservation, mastectomy, or neoadjuvant chemotherapy (3). Accordingly, precise estimation of tumor size is of utmost importance for planning a therapeutic strategy, and the main imaging modalities are mammogram (MGM), ultrasound (US), and magnetic resonance imaging (MRI). Each of these modalities has certain strengths and weaknesses in breast tumor evaluation. For instance, MGM is superior in identifying malignant calcifications; however, the obscurity of the margins and magnification variability limits the accuracy of measurements by this method (4). The sensitivity of MGM to detect malignant lesions in younger patients with dense breast tissue is also reported to be poor (5, 6). As for US, its ability to measure tumors in multiple planes is a great strength that enables a skilled operator to make measurements of its largest dimension (7). However, one main limitation of US is that it is highly operator dependent (8). MRI also offers the merit of multiplanar imaging along with a higher accuracy in assessing multicentric and multifocal lesions (9, 10); however, MRI has been reported to overestimate tumor size (9, 11), and the extent of background parenchymal enhancement (BPE) affects its accuracy (12).In this regard, studies have assessed the accuracy of tumor size estimation by MGM and US (11,[13][14][15], and compared their measurements with those by MRI (10,16,17). In comparing US and MGM, some studies have reported that US has a higher accuracy than MGM (7, 11,

Background Abbreviated magnetic resonance imaging (MRI) includes fewer sequences than standard MRI, which could be utilized for breast cancer detection. Purpose To evaluate the diagnostic accuracy of abbreviated MRI protocol in screening and diagnostic settings. Material and Methods All women with screening and diagnostic (problem-solving and preoperative staging) MRI examination were recruited from 2017 to 2020. Two expert radiologists assessed designed abbreviated protocol (fat-saturated T1-weighted [T1W] pre-contrast and two first fat-saturated T1W post-contrast series with reconstruction of their subtraction) including maximum intensity projection (MIP) and then evaluated standard protocol of breast MRI. Associated findings, including axillary lymphadenopathy and invasion to nipple, skin, or pectoralis muscle were also evaluated. The concordance rate of abbreviated with standard protocol in screening and diagnostic settings were also compared, based on BI-RADS classification. Diagnostic accuracy, sensitivity, specificity, and positive and negative predictive value were calculated. Results A total of 108 (26.5%) of 408 patients (mean age = 43 ± 9 years) were classified as BI-RADS 4–5 and considered positive findings based on suspicious enhancement (mass or non-mass enhancement). Compared to standard protocol, abbreviated protocol revealed >98% accuracy in the diagnostic setting as well as 100% accuracy in the screening setting. Concordance rates in screening and diagnostic settings were 99.6% and 98.1%, respectively. There was no discordance between abbreviated and standard protocol in the evaluation of associated findings. Conclusion Abbreviated MRI protocol possesses substantial diagnostic accuracy in both screening and diagnostic settings. Additional information provided by standard protocol might not require for cancer detection.

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now a global threat. Various papers have addressed the pulmonary symptoms of this viral disease. Also, thrombotic complications have been highly prevalent among COVID-19 patients. Reports on rare presentations of COVID-19 can help fast diagnosis and management. In this study, a COVID-19 patient is presented who developed mesenteric ischemia.