Background
Chlorfenapyr is a widely used pesticide and is classified as moderately
hazardous to human health. Ingestion usually leads to mortality in humans.
However, chlorfenapyr toxicity has a variable course and mechanism of
action.
Case presentation:
We report the case of a 79-year-old female
who ingested chlorfenapyr with the intent to commit suicide. The liquid was
ingested 2 hours before she was brought to our emergency department. Gastric
lavage was immediately performed. On admission, laboratory examinations
revealed mildly elevated liver enzyme and creatinine kinase levels. Acute
fever occurred on day 7; on day 8, the patient died of progressive
respiratory distress and conscious disturbance. Chlorfenapyr toxicity leads
to high rates of mortality (75%) and causes damage to the liver and the
nervous system.
Conclusions
It is necessary to observe patients with chlorfenapyr toxicity for 3 weeks
because no significant abnormalities occur in the early phase. The onset of
fever and deterioration of consciousness is a warning sign of a sudden fatal
outcome. We review the literature and discuss neurologic and cardiopulmonary
impairment in the clinical course of chlorfenapyr poisoning.
BACKGROUND
Vibrio pararhaemolyticus
(
V. parahaemolyticus
), a pathogen that commonly causes gastroenteritis, could potentially lead to a pandemic in Asia. Its pathogenesis and molecular mechanisms vary, and the severity of illness can be diverse, ranging from mild gastroenteritis, requiring only supportive care, to sepsis.
CASE SUMMARY
We outline a case of a 71-year-old female who experienced an acute onset of severe abdominal tenderness after two days of vomiting and diarrhea prior to her emergency department visit. A small bowel perforation was diagnosed using computed tomography. The ascites cultured revealed infection due to
V. parahaemolyticus
CONCLUSION
Our case is the first reported case of
V. parahaemolyticus
-induced gastroenteritis resulting in small bowel perforation.
Background: Tentorial dural arteriovenous fistula is a rare subtype of intracranial dural arteriovenous fistula (DAVF) with a deteriorating natural course, which may be attributed to its pial angioarchitecture. TDAVF often harbors feeders arising from pial arteries (FPAs). Reports have revealed that, if these feeders are not obliterated early, the restricted venous outflow during the embolization process may cause upstream congestion in the fragile pial network, which increases the risk of hemorrhagic complications. Because most reported cases of TDAVF were embolized through feeders from non-pial arteries (FNPAs), little is known of the feasibility of direct embolization through FPAs.Methods: We present three patients with medial TDAVFs that were embolized through the dural branches of the posterior cerebral and superior cerebellar arteries. Findings from brain magnetic resonance imaging, computed tomography, angiography, and clinical outcomes are described. Furthermore, we performed a review of the literature on TDAVFs with FPAs.Results: The fistulas were completely obliterated in two patients; both recovered well with no procedure-related complications. The fistula was nearly obliterated in one patient, who developed left superior cerebellum and midbrain infarct due to the reflux of the embolizer into the left superior cerebellar artery. Including our cases, eight cases of TDAVFs with direct embolization through the FPAs have been reported, and ischemic complications occurred in three (37.5%).Conclusions: Advancing microcatheter tips as close to the fistula point as possible and remaining highly aware of potential embolizer flow back into the pial artery are key factors in achieving successful embolization. Balloon-assisted embolization may be an option for treating TDAVFs with FPAs in the future.
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