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This study evaluated the effects of lidocaine-magnesium blood cardioplegia on left ventricular function compared with potassium blood cardioplegia. Crystalloid cardioplegia which contains lidocaine has been reported but blood cardioplegia is rare. Thirteen dogs received 60 min of global ischemia under hypothermic cardioplumonary bypass (30 degrees C). Potassium blood cardioplegia was administered every 20 min in group A (n=6), and lidocaine-magnesium blood cardioplegia in group B (n=7). We compared the ratio of Emax obtained during IVC occlusion at pre- and post-global ischemia (%Emax) and LVSW (%LVSV). Cardiac function was evaluated prior to CPB and 60 min after reperfusion. There was no difference in time required for cardiac arrest between the two groups (group A: 78+/-3 s, group B: 89+/-9 s). Percentage maximal elastance was significantly better in group B (group A: 63+/-3%, group B: 76+/-4%, P<0.05). Percentage tissue water content of the myocardium after CPB was significantly lower in group B (group A: 82.3+/-4%, group B: 75.5+/-2%, P<0.05). Lidocaine-magnesium blood cardioplegia was equivalent to potassium blood cardioplegia in systolic left ventricular function and reduced myocardial edema in canine heart.

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So that satisfactory vessel immobilization can be achieved, enabling consistently accurate grafting during off-pump coronary artery bypass grafting (CABG), mechanical immobilizing devices 1-3 have been developed along with immobilization methods including pharmacologic control of heart rate to produce bradycardia 2

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An ultra-short acting glycoprotein IIb/IIIa antagonist, FK633, is effective in preventing both platelet aggregation and thrombocytopenia during CPB, and may be effective for minimizing postoperative bleeding.

Objective Since 1999, the authors of this study have performed total endoscopic beating-heart coronary artery bypass. They have developed a new three-dimensional (3D) endoscopic imaging system and have used it successfully in three patients. Methods From January 2004, a new 3D endoscopic imaging system was used. This device, composed of an optical high-resolution, 3D endoscope and two liquid crystal monitors, gives bright, natural, 3D imaging and enables quick, precise manipulation. After the 15-mm port for the 3D endoscope was inserted through fourth intercostal space (ICS) in the posterior axillary line, the left internal thoracic artery (LITA) was taken down endoscopically in semiskeletonized fashion, using two instrumental 5-mm ports (third and sixth anterior axillary ICS). The pericardium was then opened, and the left anterior descending artery was identified. Another 10-mm port for an endoscopic needle holder was inserted through fourth ICS in the midclavicular line. Three ports were placed in the fourth ICS in line for the anastomosis. An original suction stabilizer was inserted through the first instrumental port, and the left anterior descending artery was immobilized. A conventional end-to-side anastomosis was done with 8–0 Prolene running sutures. Results The average LITA harvesting time was significantly shortened from 68 minutes with two-dimensional imaging to 36 minutes with new 3D imaging. The average anastomotic time was shortened from 34 minutes with two-dimensional imaging and 27 minutes with former 3D imaging to 17 minutes with new 3D imaging. There were no complications and no operative deaths. Conclusions This new 3D endoscopic imaging system facilitates quick, precise anastomosis and is a useful device for endoscopic coronary bypass surgery.