Purpose: To assess the diagnostic accuracy of multi-detector CT angiography in the assessment of lower extremity arterial diseases by comparing the results with the standard of reference, conventional angiography. Patients and Methods: The studied group included 140 patients with suspected diagnosis of lower limb arterial disease on the basis of clinical examination or Doppler study with no age or sex predilection between March 2011 and November 2013. All patients were evaluated with lower limb angiography by multi-detector computed tomography and conventional angiography. The data obtained was statistically analysed to assess the accuracy of diagnosis of lower limb arterial diseases by MDCT angiography compared to conventional angiography that described in terms of count and percentage. Results: MDCT angiography findings showed 90.3% overall agreement with CA findings regarding the degree of stenosis while regarding the stenosis length MDCT angiography results showed 87.5% overall agreement with CA results. The overall sensitivity of MDCT angiography was 94.5%, specificity was 92.2%, and accuracy was 95.3%. Conclusion: Multi-detector row CT angiography can be used as an alternative to conventional angiography in the evaluation of aortoiliac and lower extremity arteries in patients with peripheral arterial disease.
Background: Diffusion weighted magnetic resonance imaging (DW-MRI) is a functional, non-invasive imaging technique which generates tissue contrast from differences in mobility of water molecules that occurs during an MR pulse sequence. Information regarding the integrity of cellular membranes and tissue cellularity can be obtained, so that DW-MRI can now be included in routine patient assessment. Aim of the Work: The aim of this study is to evaluate the role of DW-MRI in the diagnosis of cervical carcinoma, with pathological diagnosis was taken as the reference. Patients and Methods: This is a retrospective study that included 20 patients in whom cervical cancer had been suspected clinically or by transvaginal ultrasound (U/S) and the control group consisted of 20 patients in whom cervical cancer had not been suspected and MRI was performed because of other Pelvic diseases. The study was conducted in El-Demerdash Hospital. The patients were referred from the Gynecology Department to the Radiology Department (Women's imaging unit) for further MRI assessment with diffusion weighted images (DWIs). Results: Lesions in all cases show restricted diffusion, however on apparent diffusion coefficient (ADC) map, only one case showed high signal proved to be chronic cervicitis on histopathology. Also, the mean ADC values for malignant lesions were (0.82 x10-3 mm 2 /sec), while the mean ADC value in the control group was (1.58x10-3 mm 2 /sec). Therefore ADC value of (1.04 x10-3 mm 2 /sec) is a cut off between normal cervical tissue and malignant cervical lesion by sensitivity 95% and specificity 95 %. DWIs had elicited the same accuracy to Dynamic contrast-enhanced (DCE) sequences (95%) when added to the non-contrast MRI in the estimation of cancer cervix. Conclusion: Our results proved that (DW-MRI) was significantly beneficial in terms of diagnostic performance that increases the radiologist's confidence in image interpretation. So it implies a non-invasive technique which can be used especially if contrast intake is avoided as in pregnancy. Thus, we suggest that DWI should be included in the routine pelvic MRI protocol. The ADC value in case of cervical carcinoma was significantly lower than in the normal cervical tissue. The ADC threshold of (1.04 x10-3 mm 2 /sec) was a cut off value, which was detected when differentiating between cancer-affected and non-affected cervical tissues
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.