Every measure should be taken to avoid the occurrence of bowel injury during laparoscopy. Intraoperative or early postoperative diagnosis and proper management of laparoscopic-induced bowel injuries can minimize morbidity and mortality and yield a better prognosis.

No abstract

No abstract

Background:: The unusual pneumonia outbreak that originated in the city of Wuhan, China in December 2019 was found to be caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or COVID-19. Methods:: In this work, we have performed an in silico design and prediction of potential siRNAs based on genetic diversity and recombination patterns, targeting various genes of SARS-CoV-2 for antiviral therapeutics. We performed extensive sequence analysis to analyze the genetic diversity and phylogenetic relationships, and to identify the possible source of virus reservoirs and recombination patterns, and the evolution of the virus as well as we designed the siRNAs which can be used as antivirals against SARS-CoV-2. Results:: The sequence analysis and phylogenetic relationships indicated high sequence identity and closed clusters with many types of coronavirus. In our analysis, the full-genome of SARS-CoV-2 showed the highest sequence (nucleotide) identity with SARS-bat-ZC45 (87.7%). The overall sequence identity ranged from 74.3% to 87.7% with selected SARS viruses. The recombination analysis indicated the bat SARS virus is a potential recombinant and serves as a major and minor parent. We have predicted 442 siRNAs and finally selected only 19 functional, and potential siRNAs. Conclusions:: The siRNAs were predicted and selected based on their greater potency and specificity. The predicted siRNAs need to be validated experimentally for their effective binding and antiviral activity.

Background: The coronavirus disease 2019 pandemic has claimed many lives and strained the US health care system. At Boston Medical Center, a regional safety-net hospital, the Department of Surgery created a dedicated coronavirus disease 2019 Procedure Team to ease the burden on other providers coping with the surge of infected patients. As restrictions on social distancing are lifted, health systems are bracing for additional surges in coronavirus disease 2019 cases. Our objective is to quantify the volume and types of procedures performed, review outcomes, and highlight lessons for other institutions that may need to establish similar teams. Methods: Procedures were tracked prospectively along with patient demographics, immediate complications, and time from donning to doffing of the personal protective equipment. Retrospective chart review was conducted to obtain patient outcomes and delayed adverse events. We hypothesized that a dedicated surgeon-led team would perform invasive bedside procedures expeditiously and with few complications.

Although varicose vein surgery is safe, acceptable and cost-effective as a day case procedure, if attempted in all-comers, overnight admission will be required in a significant proportion. Pre-operative selection is advised.

Background: Although successful retirement planning improves the well-being of retiring surgeons and facilitates effective succession strategies, the status of retirement mentoring in academic surgery remains unknown. The present study was designed to evaluate the presence of mentoring for retirement in the departments of surgery in the United States. Material and methods:A survey consisting of 5 questions (2 multiple choice; 3 yes/no) was sent to 170 chairs of departments of surgery in the United States in March 2019 regarding the presence and structure of mentoring for retirement in their department and their attitude towards retirement mentoring. The analysis of the data was performed in April 2019.Results: A total of 53 of 170 surveys were completed (31.2% response rate). There was no mandatory retirement age in any of the participating departments of surgery. Only two of 53 department chairs (3.8%) reported having an established mentorship for retirement for their senior faculty. At both departments mentoring for retirement consisted in informal pairing of mentors with mentees, without any financial support for the mentorship. Most department chairs [42 of 53; (79.2%)] considered retirement mentoring beneficial for senior faculty nearing retirement. Only 7 (13.2%) respondents found retirement mentoring not necessary as they believe senior surgeons have sufficient life experience and social support to deal with transition into retirement. Out of 42 respondents who found mentoring for retirement important, the vast majority (36; 85.8%) believe that it should be formally provided

No abstract