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BACKGROUND: Carbon dioxide fixation by microalgae is a promising biotechnology for reduction of CO 2 emissions, however, the photosynthetic process of microalgae is inhibited by excessive dissolved oxygen, especially in enclosed photobioractors. In this study, a consortia of microalgae and yeast was used to investigate the effect of yeast on biomass production, photosynthetic activity and CO 2 biofixation rate in the microalgae.