Here, we introduced a novel thiourea-based rhodamine compound as a chromo-fluorogenic indicator of nerve agent Soman and its simulant diethyl chlorophosphate (DCP). The synthesized probe N-(rhodamine B)-lactam-2-(4-cyanophenyl) thiourea (RB-CT), which has a rhodamine core linked by a cyanophenyl thiosemicarbazide group, enabled a rapidly and highly sensitive response to DCP with clear fluorescence and color changes. The detection limit was as low as 2 × 10−6 M. The sensing mechanism showed that opening of the spirolactam ring following the phosphorylation of thiosemicarbazides group formed a seven-membered heterocycle adduct, according to MS analysis and TD-DFT calculations. RB-CT exhibited high detecting selectivity for DCP, among other organophosphorus compounds. Moreover, two test kits were employed and successfully used to detect real nerve agent Soman in liquid and gas phase.

Supraparticles (SPs) are agglomerates of smaller particles, which show promising applications in catalysis, sensing, and so forth. Preparation of SPs with controlled sizes, components, and structures in an efficient, scalable, and environmentally friendly way has become an urgent demand for the development of SPs. Herein, a method to fabricate SPs based on the Leidenfrost phenomenon is described. By dropping a nano-/ microparticle dispersion on a metal plate at the Leidenfrost temperature (T LF ) or higher, the solvent evaporates quickly, and SPs can be formed within 1 min. To understand the influence of various factors on the properties of SPs, and also to optimize the fabrication of SPs, the effects of metal surface roughness and primary particle concentration on T LF were carefully observed. Plates with a higher roughness as well as a higher primary particle concentration could trigger a lower T LF . Combining the regulation of composition and volume of the droplets, SPs with different sizes, compositions, and structures were precisely fabricated. Furthermore, highly porous titanium dioxide (TiO 2 ) SPs with enhanced photocatalytic performance were fabricated via this method, showing the merits of the method in practical applications. This simple, efficient, and green method provides a new approach for controlled and large-scale fabrication of SPs with various functions.

The ultra-high capacity of silicon (Si) holds great promise for high-energy density Li-ion batteries. Unfortunately, effective dissipation of mechanical stress of Si while improving conductivity remains a great challenge. Here,...

Objective This study aimed to investigate the clinical efficacy of closed reduction high-strength sutures combined with Nice knots in treating transverse patella fractures. Method We retrospectively analyzed the clinical data of 28 patients who underwent surgery for transverse patella fractures from January 2019 to January 2020. Twelve cases of the study group were treated with closed reduction high-strength sutures combined with Nice knots, and 16 cases in the control group were treated with tension band wiring. Observations included patellar healing, follow-up knee mobility with Böstman score, Lysholm score, surgical data, postoperative complications, and secondary surgery rate. Result No statistically significant difference was observed between the two groups in the Patient demographic data, with a mean follow-up of 13.14 ± 1.58 months. There was no delayed healing or deep infection in the two groups. In the control group, 2 cases of internal fixation failure and 1 case of superficial infection were observed. The differences in mean fracture healing time, follow-up Böstman score, Lysholm score and knee mobility between the two groups were not statistically different. However, the differences were statistically significant for the duration of surgery, Incision length, intraoperative bleeding and the secondary surgery rate was lower in the study group. Conclusion Closed reduction high-strength sutures have good clinical efficacy in treating transverse patella fractures, with the advantages of shorter duration of surgery and Incision length,less intraoperative bleeding and no secondary removal.

No abstract