Highlights d 11 neutralizing antibodies against SARS-CoV-2 target three main epitopes on RBD d Epitope-A antibody 414-1 shows neutralizing IC 50 at 1.75 nM d Epitope-B antibody 553-15 can enhance the neutralizing abilities of other antibodies d One neutralizing antibody, 515-5, can cross neutralize SARS-CoV pseudovirus

Highlights d METTL5 shows strong substrate preference to 18S rRNA m 6 A1832 motif UAACA d The m 6 A1832 modification may affect decoding center in favoring mRNA binding d METTL5 promotes translation initiation, S6K activation, and breast cancer cell growth d C. elegans METL-5 regulates stress response, lifespan, and UPR ER

No abstract