Traditional wound care methods include wound infection control, adequate nutritional supplements, education of changing position every 2-3 h to avoid tissue hypoxia, vacuum assistant closure, debridement, skin graft, and tissue flap. Electric current stimulation, ultrasound, laser, and hydrotherapy have emerged as adjuvant therapies. However, most, if not all, of these therapies are expensive, and the treatment results are variable. The development of the active methods to improve wound healing is mandatory. CO administration has been known to improve microcirculation and local oxygen supply that are beneficial to wound healing. Here, the metal ion-ligand coordination nanoarchitecture was designed to reveal NIR light-induced CO generation for wound healing. The administration simply topically dropped the colloidal solution on the incisional wound, followed by exposure of near-infrared (NIR) lamp to yield CO, resulting in the observation of the accelerated wound healing.
In this paper, a dynamic stress analysis of seismic vibration isolator was carried out by using ANSYS. The vibration isolator consisted of Si-Cr springs and magnetorheological dampers. The stress and deformation of the springs were calculated when an impact load was applied to the isolator. From the simulation for six different springs, in terms of their wire dimeter and coil diameter, an optimum shape of the springs to minimize the stress and deformation was determined.
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