To protect ancient buildings from fire, prevent the occurrences of fire, and minimise the losses caused by fire to the maximum extent possible, this study combined experimental measurements and numerical simulations to analyse the flame spread behaviour over wood treated with flame retardants. First, some wood blocks were treated with a nitrogen and phosphorus (water-based) flame retardant, and then a smoke combustion experiment was performed to test the smoke density. Scanning electron microscopy was also employed to observe the flame retardant effect. Next, a fire dynamic simulation software was used to simulate and analyse the results of the flame spread behaviour over the yellow pine collected from the Long’en Hall of Fuling Mausoleum, that was treated with flame retardants. The results showed the variation trend of the fire site’s heat release rate (HRR) over time to be consistent with the movement of fire spread after its occurrence. Compared with pristine wood, the flame retardant-treated wood exhibited a HRR reduction of 53.1%. The addition of flame retardants also reduced the concentration of the released smoke and CO2 gas, decreased the temperature of the fire site, and enhanced visibility.

Background and aims Coronary in-stent restenosis (ISR) is an important complication of percutaneous coronary intervention (PCI). However, the relationship between lipoprotein associated phospholipase A2 (Lp-PLA2) level and ISR after PCI is rarely reported. This study aims to explore the relationship between Lp-PLA2 and the occurrence of ISR at post-PCI and its predictive value for ISR. Methods and results Plasma Lp-PLA2 mass were measured in 847 patients planting 1262 stents and evaluated along with known risk indicators. One-year angiographic follow-up showed that baseline elevated Lp-PLA2 mass was strongly associated with early restenosis (95% CI = 1.062-3.050, P < 0.05). Beyond the first year, the occurrence of late restenosis (95% CI = 1.043-3.214, P < 0.05) was significantly larger in the elevated Lp-PLA2 group. Kaplan-Meier analysis after three-year clinical follow up suggested that Lp-PLA2 mass did add the positive effect on the occurrence of major adverse cardiovascular events (MACEs). Conclusion In conclusion, increased baseline plasma Lp-PLA2 predicts increased risks of re-stenosis and MACEs, which may be a novel biomarker for predicting ISR and MACEs.

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