Background:The purpose of this study is attempting to the assessment of the effectiveness of low level laser therapy (LLLT) with specific parameters in the treatment of selected Sudanese patients based on clinical records of different skin ulcers and diabetic's wounds in Khartoum state hospitals. Thus, the effect of the laser treatment using biostimulation effects on tissues in infrared laser and in the visible region depends on frequencies, power density and time of exposure rate on skin diseases. Methods: It is prospective clinical descriptive, interventional study on seven selected males and females of different ages depend on clinical and positive smear LD bodied, which was confirmed at Omdurman tropical disease hospital. Low power laser Omega-XP with tunable wavelengths 820 nm, 780 nm, 675 nm and constant parameters were applied for medical treatment. Results: Utilization of laser dosage (energy density) of 40 J/cm 2 and 1.6 w/cm 2 power density of the wavelength 820 nm and 30 J/cm 2 energy density and power density of 0.24 w/cm 2 of 780 nm wavelength, in addition to energy density of 8 J/cm 2 and power density of 0.24 w/cm 2 and 0.40 w/cm 2 and energy density of 1.6 J/cm 2 for the 675 wavelength was applied. In this study, we used the bio-stimulation effect of LLLT to enhance healing through immune modulation. However, the application of low level diode laser in the treatment of diabetic wounds can be accompanied by low energy density and short wavelength to give better results in a short time and a good diagnostic accuracy for its potentiality in the field. Conclusions: Consequently, the brown skins in Sub-Saharan region for different tissues of Sudanese diabetic patients of chronic skin ulcer can be treated with different wavelengths and energy relative to tissues softening and laser parameters of that optimum values were obtained. The assessment of skin regeneration using laser therapy expose that the quality of growth, the reasonable period of healing and decreases the risk skin infection were achieved. The process of diabetic wounds curing and de-pigmentation, potential resident of decreasing pain and an efficient adjunct to a standard wound management was obtained.
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