Most unplanned readmissions to a tertiary cancer hospital are related to progression of disease, new diagnoses, and procedure complications. Minimizing readmissions in complex cancer patients is challenging. Larger multi-institutional datasets are needed to determine a reasonable standard for expected readmission rates.
Cervical near-hangings are referred to the Trauma Service for evaluation. Scene or ED GCS of 3 does not preclude neurologically intact survival, although mortality is high. In our study, the most useful prognostic factors were the need for airway control by intubation or cricothyrotomy, cardiopulmonary resuscitation, lower scene and ED GCS, and cerebral edema on CT Scan. Optimal evaluation includes head and neck CT and CT angiography of the neck. We plan to share these results with local authorities and encourage improvement in risk identification, with earlier involvement of mental health personnel.
Introduction
Patients with metastatic colorectal cancer can develop jaundice from
intrahepatic or extrahepatic causes. Currently, there is little data on the
underlying causes and overall survival after onset of jaundice. The purpose
of this study was to characterize the causes of jaundice and determine
outcomes.
Methods
Six hundred twenty-nine patients treated for metastatic colorectal
cancer between 2004 and 2010 were retrospectively reviewed. Those developing
jaundice were grouped as having intrahepatic or extrahepatic obstruction.
Demographics, clinicopathologic, and outcome data were analyzed.
Results
Sixty-two patients with metastatic colorectal cancer developed
jaundice. Intrahepatic biliary obstruction was most common, occurring in
younger patients. Time from metastatic diagnosis to presentation of jaundice
was similar between groups, as was the mean number of prior lines of
chemotherapy. Biliary decompression was successful 41.7 % of the time and
was attempted more commonly for extrahepatic causes. Median overall survival
after onset of jaundice was 1.5 months and it was similar between groups,
but improved to 9.6 months in patients who were able to receive further
chemotherapy.
Conclusions
Jaundice due to metastatic colorectal cancer is an ominous finding,
representing aggressive tumor biology or exhaustion of therapies. Biliary
decompression is often difficult and should only be pursued when additional
treatment options are available.
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