In gastroschisis, the defect in the abdominal wall is located almost always to the right of the umbilicus. Left-sided gastroschisis is a very rare entity. A case of left sided gastroschisis has been described here, with review of literature.
A 3-year-old male presented with an episode of respiratory distress that was superimposed on a 2 1/2 years history of recurrent chest infections. The chest radiograph and a contrast enhanced CT scan revealed a cystic cavity in the left upper lobe with an endobronchial soft tissue mass in left bronchus. Left bronchotomy and removal of the endobronchial soft tissue mass and left upper lobectomy were performed. The histology of the specimen revealed a pleuropulmonary blastoma (PPB) type II. The presentation, diagnosis, and management of this uncommon case of PPB with intrabronchial extension are described.
Aims:To study and compare the effects of angiotensin II antagonist (Losartan) and angiotensin converting enzyme (ACE) inhibitor (Enalapril) on renal recovery following reversal of iatrogenic unilateral upper ureteric obstruction.Materials and Methods:Unilateral upper ureteric obstruction was created in 96 adult Wistar rats that were reversed after predetermined intervals. Losartan and Enalapril were given to different subgroups of rats following relief of obstruction. Rats were sacrificed and kidneys were subjected to planimetric and histopathological analysis.Results:Dorsal lumbotomy approach provided a rapid and safe approach to kidneys in rats. The planimetric and histopathological changes were most severe in the group of rats in whom obstruction was not relieved before sacrifice. Addition of Enalapril and Losartan significantly hastened the reversal of renal changes following relief of obstruction as compared with the group in which no treatment was given following reversal of blockade.Conclusions:Renin angiotensin system (RAS) is the major pathway responsible for renal damage following outflow obstruction. However, this damage can be reversed with the use of drugs acting on the RAS.
Neonatal intussusception is rare entity.We report this very rare case of a term male newborn, with acute jejunojejunal intussusception without any lead point. He presented with abdominal distension and signs of intestinal obstruction and abdominal sonography showed a jejunojejunal intussusceptionswhich was confirmed at laparotomy. Interestingly, no lead point was found. Rather 8cm of bowel distal to intussuscepted segment was found to be gangrenous bowel. Resection with Bishop Koop anastomosis done for the baby resulted in good outcome. The case is being presented for rare presentation of a rare surgical condition in a neonate with an endeavour to establish etiology for its occurrence.
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