Background Pulse oximeters measure oxygen saturation, heart rate, and perfusion index (PI) by analyzing photoplethysmographic signals. PI is an indirect measure of peripheral perfusion expressed as a percentage of pulsatile signals to non-pulsatile signals. PI measured from different sites may show variation. PI may vary when measured on different fingers. In this study, we aimed to observe the variation of PI among different fingers of both hands. Methodology This cross-sectional, observational study was conducted using a convenience sample recruited from a tertiary care hospital in eastern India. PI was measured in apparently healthy adults in a sitting posture after a five-minute rest. The pulse oximeter probe was attached to each finger and readings were taken after one minute. The analysis of variance and intraclass correlation coefficient (ICC) were calculated to compare and find agreement among PI. Results Data from a total of 391 (229 [58.57%] male and 162 [41.43%] female) adult research participants with a mean age of 34.88 ± 10.65 years were analyzed. The PI was the highest on the middle finger in both hands. There was a significant difference among the PI measured on different fingers, F (9, 3900) = 15.49, p <0.0001. The ICC was 0.474, 0.368, and 0.635 for overall, right-hand, and left-hand fingers, respectively, which indicate poor (ICC < 0.5) to moderate (ICC = 0.5-0.75) levels of reliability. Conclusions The PI measured using consumer-grade pulse oximeters on different fingers may provide different readings. The highest PI reading is found on the middle finger. Clinicians and primary care physicians should consider the differences in measured PI among different fingers and should use the readings with caution for any diagnostic purposes.
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