Background To systematically analyze the evaluation indexes of injury degree and prognostic improvement in traumatic spinal cord injury. Methods A retrospective analysis of 133 patients with traumatic spinal cord injury admitted to our hospital from January 2017 to August 2021. The clinical indicators collected include the following: patient gender, age, underlying diseases, time from trauma to operation, length of hospital stay, intraoperative blood loss, cause of injury, whether accompanied with (or multi-segment ) spinal fracture and dislocation, intervertebral disc herniation, other sites of the injury and complications, the type of complications, spinal cord injury plane, surgical methods, ASIA grade within 72h and 6 months after injury, whether received hyperbaric oxygen therapy or high-dose cortisol hormone therapy, mean arterial pressure 3 days after operation, neutrophil/lymphocyte ratio (NLR) within 72h after admission, the length of MR spinal signal change, maximum canal compression (MCC), maximum spinal cord compression (MSCC), and the BASIC score of spinal signal changes. Results 1) The length of signal change (p < 0.001), MSCC (p < 0.05), MCC (p < 0.05) and NLR within 72h of injury (p < 0.01) were significantly different among groups with different degrees of TSCI injury. 2) MAP (p༜0.01), NLR (p༜0.01), and the initial degree of injury (p༜0.05) showed significant differences between the groups of patients with improved and non-improved prognoses 6 months after TSCI injury. Conclusions The MRI signal change length, MSCC, MCC, and NLR within 72 h after injury are good indicators of the TSCI severity while MAP, NLR, and ASIA can be used to evaluate the prognosis of TSCI patients.
To study the epidemiological characteristics of traumatic spinal cord injury (TSCI) in Guangzhou, China, and identify high-risk population, so as to provide reference for prevention, diagnosis and treatment of SCI. Methods: The First Affiliated Hospital of Jinan University between January 2017 and December 2020 hospitalized patients with spinal cord injury were analyzed retrospectively, and observe the following relevant factors: age, gender, injury time, injury causes, segmental spinal cord injury, whether with spine fracture, whether to merge with other parts of the injury, whether complications. The above indicators were analyzed statistically. Results: There were 197 patients with spinal cord injury, the male to female ratio was 2.72:1. The average age was 47.83±13.70 years from 5 to 80 years old, and the patients aged from 41 to 50 years old were the most (28.0%). The main causes of injuries were falls (33.0%), falls (32.0%), traffic accidents (26.9%), and heavy injuries (7.1%). The incidence of lumbar spinal cord injury was the highest, followed by cervical spine injury. Complications occurred during hospitalization in 51.3% of TSCI patients, with pulmonary infection accounting for 34.8%, followed by urinary tract infection accounting for 25.6%. The higher the severity of spinal cord injury, the higher the probability of complications, the incidence of complications in ASIA grade A patients was 96%. Class B 73.3%; Grade C 59.1%, D 29.6%. Conclusion: Young and middle-aged men are the high risk group of TSCI, and the main causes of injury are fall injury, fall injury and car accident injury. The incidence of spinal cord injury was highest in lumbar vertebra L1 and L2, cervical vertebra C4 and C5, and thoracic vertebra T12 and T11. Complications occurred during hospitalization in 51.3% of TSCI patients, with pulmonary infection being the most common, followed by urinary tract infection. The higher the severity of spinal cord injury, the greater the probability of complications.
Background To systematically analyze the evaluation indexes of injury degree and prognostic improvement in traumatic spinal cord injury. Methods A retrospective analysis of 133 patients with traumatic spinal cord injury admitted to The First Affiliated Hospital of Jinan University from January 2017 to August 2021. The clinical indicators collected include the following: patient gender, age, underlying diseases, time from trauma to operation, length of hospital stay, intraoperative blood loss, cause of injury, whether accompanied with (or multi-segment ) spinal fracture and dislocation, combined disc herniation or not, other sites of the injury, the type of complications, spinal cord injury site, surgical methods, ASIA grade within 72 hours and 6 months after injury, whether received hyperbaric oxygen therapy or high-dose cortisol hormone therapy, mean arterial pressure 3 days after operation, neutrophil/lymphocyte ratio (NLR) within 72h after admission, the length of MR spinal signal change, maximum canal compression (MCC), maximum spinal cord compression (MSCC), and the BASIC score of spinal signal changes. The SPSS software was used to perform Student t-test, Chi-square test, and Logistic regression analysis on the above indicators to find the factors associated with injury severity and prognosis. Results 1) The length of signal change (p < 0.001), MSCC (p < 0.05), MCC (p < 0.05) and NLR within 72h of injury (p < 0.01) were significantly different among groups with different degrees of TSCI injury. 2) MAP (p<0.01), NLR (p<0.01), and the initial degree of injury (p<0.05) showed significant differences between the groups of patients with improved and non-improved prognoses 6 months after TSCI injury. Conclusions The MRI signal change length, MSCC, MCC, and NLR within 72 h after injury are good indicators of the TSCI severity while MAP, NLR, and ASIA can be used to evaluate the prognosis of TSCI patients.
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