Adenomyoma is a benign tumor composed of endometrial glands, specialized endometrioid stroma, and smooth muscle. These tumors typically originate within the uterus. An extrauterine adenomyoma is an extremely rare entity. We present the case of a 56-year-old perimenopausal woman with a right adnexal mass, diagnosed histopathologically as an ovarian ligament adenomyoma. This report documents a fourth case of an extrauterine adenomyoma and only the second case in ovarian ligament. The differential diagnosis includes endometrioma, leiomyomatosis peritonealis disseminata, uterus-like mass lesion and extrauterine leiomyoma with entrapped endometrioid glands and stroma. Two theories for the etiology of adenomyoma have been proposed: (i) Müllerian duct fusion defect and (ii) metaplasia.
Clear-cell meningioma (CCM), an unusual subset of meningioma has prominent, clear-cell morphology. It is a wolf in sheep's clothing characterized by benign histologic attributes, but tendency for recurrence (61%) and metastasis. Therefore, WHO has classified it as grade II meningioma. Fine-needle aspiration cytology diagnosis is simple, rapid, cost-effective and reliable procedure primarily aimed at preoperative diagnosis of advanced and metastatic extracranial tumor. Preoperative and/or intraoperative cytodiagnosis of CCM demand expertise in the evaluation of cytology smears. However in case of intra operative evaluation of squash smears there is a time constraint and a very small tissue material obtained by stereotactic biopsy are available for interpretation. Knowledge of clinical features including age, anatomical locations, neuroimaging findings and cytomorphologic features, are prerequisites for arriving at definitive cytodiagnosis. We describe intra operative squash cytology of CCM in a 16-year-old female, located in cerebello-pontine angle. The diagnosis of CCM offered on squash cytology was subsequently confirmed on histopathology and immunohistochemistry. It typically showed pattern less sheets and groups of polyhedral, clear cells with monomorphic, round nuclei having a bland chromatin and inconspicuous nucleoli. Separation of CCM from other tumors having clear -cell morphology and variants of meningioma is important because of its high recurrence rate and mortality.
Introduction: The spinal meningeal lesions are a distinct and interesting group of lesions with a wide spectrum of clinical and histological presentation. The aim of our study was to analyse the clinic-radiological spectrum of spinal meningeal lesions with histopathological correlation. Methods: Our study comprised of 88 cases of spinal meningeal lesions over a consecutive 10 years period in tertiary care hospital. Descriptive cross-sectional study of cases including detailed clinical data of age, sex, duration of disease, type of lesion, and radiological findings of the patients was obtained. The analysis of all the cases was done by examining Hematoxylin and Eosin stained slides with use of special stains and immunohistochemistry, if needed. Results: Male predominance was seen in spinal meningeal lesions with M: F ratio of 1.2:1 with 3rd and 4th decade age group was most commonly affected. These lesions were common in thoracic region followed by lumbar region .Neoplastic lesions of spinal meninges were more frequently encountered than non-neoplastic lesions. Meningioma (37.50 %) was the most common spinal meningeal tumor followed by lipoma (18.18 %). Psammomatous meningioma (45.45 %) was the most commonly observed histological type of meningioma. Epidermoid and dermoid cysts (23.92 %) were the most common cystic (non-neoplastic) meningeal lesions. Conclusion: Considering the rarity of spinal meningeal lesions, a multidisciplinary approach with the combination of clinical, radiological, and histopathological features forms the basis of its diagnostic approach.
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