The central role of vitamin D in calcium homeostasis is to increase calcium absorption from the intestine. This article describes the early work that served as the foundation for the initial model of vitamin D mediated calcium absorption. In addition, other research related to the role of vitamin D in the intestine, including those which have challenged the traditional model and the crucial role of specific calcium transport proteins, are reviewed. More recent work identifying novel targets of 1,25(OH) 2 D 3 action in the intestine and highlighting the importance of 1,25(OH) 2 D 3 action across the proximal/distal and crypt/villus axes in the intestine is summarized.
Objective We investigated factors affecting the disability assessment Longshi scale, and differences between the Longshi and Barthel scales, as well as modified Rankin scale (mRS), to determine whether the Longshi scale is superior to the other scales. Methods This cross-sectional study included 721 participants with disability. We performed the t-test, analysis of variance, Pearson’s correlation test, and multiple linear regression to analyze group differences and define explanatory variables. Results The Longshi scale had a strong positive correlation with the Barthel scale (r = 0.868) but a weak negative correlation with the mRS (r = –0.185). Scores obtained among seven study hospitals in two provinces of southeast China were significantly different (F = 8.034). Social activities of participants with disability can be positively predicted using the Longshi (β = 0.251) and Barthel scales (β = 0.276). However, age has a weak negative correlation with the Longshi scale (r = –0.163). Conclusion Training did not cause significant variations in assessment using the Longshi scale. However, the results differed among different regions. The Longshi scale showed a strong correlation with the Barthel scale but a weak correlation with the mRS. Assessment time was shorter using the Longshi scale and the scale can be used to predict the social activities of individuals with disability.
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