For critically ill adults, oxygen saturation is continuously monitored using pulse oximetry (Spo 2 ) as a surrogate for arterial oxygen saturation (Sao 2 ). Skin pigmentation may affect accuracy of Spo 2 by introducing error from statistical bias, variance, or both. We evaluated relationships between race, Spo 2 , Sao 2 , and hypoxemia (Sao 2 < 88%) or hyperoxemia (Pao 2 > 150 mm Hg) among adults receiving mechanical ventilation in a medical ICU. DESIGN:Single-center, observational study. SETTING: Medical ICU at an academic medical center.PATIENTS: Critically ill adults receiving mechanical ventilation from July 2018 to February 2021, excluding patients with COVID-19, with race documented as Black or White in the electronic medical record, who had a pair of Spo 2 and Sao 2 measurements collected within 10 minutes of each other. INTERVENTIONS:None. MEASUREMENTS:We included 1,024 patients with 5,557 paired measurements within 10 minutes, of which 3,885 (70%) were within 1 minute. Of all pairs, 769 (14%) were from Black patients and 4,788 (86%) were from White patients. In analyses using a mixed-effects model, we found that across the range of Spo 2 values of 92-98%, the associated Sao 2 value was approximately 1% point lower for Black patients compared with White patients. Among patients with a Spo 2 value between 92% and 96%, Black patients were more likely to have both hypoxemia (3.5% vs 1.1%; p = 0.002) and hyperoxemia (4.7% vs 2.4%; p = 0.03), compared with White patients.CONCLUSIONS: Among patients with a measured Spo 2 of 92-96%, greater variation in Sao 2 values at a given Spo 2 resulted in a higher occurence rate of both hypoxemia and hyperoxemia for Black patients compared with White patients.
Over six percent of the American population experience homelessness in their lifetime, and poor health is commonplace among individuals experiencing this condition. Homelessness is a risk factor for both acute and chronic diseases; homeless populations experience an age-adjusted mortality rate 3-4 times greater than the general population. In fact, despite the high prevalence of poor health behaviors and the well-documented disparities in health care outcomes among homeless adults, interventions for this population are scarce, likely due to the fact that they are challenging to implement. Consequently, there are few published interventions on diet/physical activity interventions targeting this population to date. Health-eStrides, a novel randomized pilot lifestyle intervention for 32 transitional shelter residents, took place at The Bridge in Dallas, Texas. This paper reports on the lessons learned and approaches for intervening in this vulnerable population.Participants were randomized into either the experimental arm or control arm of the study. The experimental arm included a 4-week shelter-based diet, physical activity intervention, tailored educational newsletters, and supplemental fruits and vegetables; the control arm was not given any additional resources and compensated for completing assessments at the conclusion of the study. 71% of participants reported that the intervention was "extremely/very helpful" for both increasing daily intake of fruits and vegetables and for increasing physical activity.Based on this intervention, this paper discusses barriers and facilitators for lifestyle improvements among homeless adults. This intervention demonstrated the effectiveness of customized lifestyle interventions in improving health care outcomes for homeless adults and affirms the need for more research and innovation on this vulnerable population, especially in terms of long-term and sustainable solutions.
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