Women carrying pathogenic sequence variants (PSVs) in BRCA1 and/or BRCA2 genes are at a substantially increased risk of developing breast, ovarian, fallopian tube, and primary peritoneal cancers compared with average risk women. 1 Although screening programs may facilitate early detection of breast cancer, there are currently no effective screening means for early detection of ovarian cancer. Surgical risk-reducing bilateral salpingo-oophorectomy (RRBSO) is the only established means to actively reduce ovarian cancer risk among BRCA1 and BRCA2 PSV carriers. 2 Therefore, the guidelines of professional societies advocate that BRCA PSV carriers should
Hysteroscopy, is a technique by which we can look into the uterine cavity entering through the cervix and is today the most applied minimally invasive technique in Gynecology. Indications for hysteroscopy include infertility investigation, abnormal uterine bleeding, and evaluation of suspicious sonographic findings. Nowadays we approach the uterus via vaginoscopy with no anesthetic. Once inside the uterus, we remove polyps or stringless IUD and take a biopsy. These procedures are often referred as “see and treat”. Operative hysteroscopy under GA or sometimes cervical block, uses larger instruments to resect myomas, cut a septum (metroplasty) or separate intrauterine adhesions (Asherman’s). As Glycine is no more used in hysteroscopy it has become quite a safe procedure. Use of disposable scopes will enable this tool to be part of every gynecologic clinic.
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