No abstract

No abstract

An efficient and green one-pot method for the oxidative aromatization and bromination of pyrazolidin-3-ones under mild conditions with a HBr-H2O2 system was developed. A mechanism was proposed.

A convenient and economical one-pot synthesis of a series of new 1-aryl-substituted 4-iodopyrazole-3-ols from easily available pyrazolidin-3-ones in the presence of sodium iodide, 30% solution of hydrogen peroxide and a catalytic amount of sulfuric acid in dichloromethane via aromatisation and oxidative iodination reactions are described. This protocol has the advantages of high atom economy, cost-effectiveness, short reaction time and environmental friendliness.

Four binary co-crystals were mainly formed by halogen bonds and charge transfer interactions, which generated remarkable optical properties.