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This study aims to determine the asymptomatic bacteriuria in pregnancy due to GBS and its antimicrobial sensitivity pattern for planning strategy for the management of these cases and also to determine the relationship between asymptomatic bacteriuria and pyuria. A total of 3863 consecutive urine specimens were collected from 3863 pregnant women with asymptomatic bacteriuria attending the obstetrics and gynaecology department of our hospital over a period of two years. Specimens were processed using standard microbiological procedures. All the subjects were evaluated for bacteriuria. The prevalence of asymptomatic bacteriuria due to group B streptococci (GBS) was 82/3863 (2.1%) among pregnant women in Saudi Arabia. Among these, 69/82 patients (84.2%) had clinical and microbiological features consistent with cystitis, versus 13/82 (15.8%) for pyelonephritis. About 51.2% (42/82) of the patients who had urine analysis performed had positive results based on positive urinary leucocyte esterase and pyuria. Disc-diffusion analysis of all 82 GBS isolates showed that they were highly susceptible to Augmentin and linezolid. Screening for bacteriuria in pregnancy and proper treatment must be considered as an essential part of antenatal care in this community. To prevent asymptomatic bacteriuria complications, all pregnant women should be screened at the first antenatal visit. A negative test for pyuria is not a reliable indicator of the absence of asymptomatic bacteriuria in pregnant women. Further, ongoing surveillance and evaluation of outcomes in pregnancies complicated by GBS bacteriuria is required to optimise maternal and newborn care.

Keywords: Antibiotic; Armed Forces Hospital; Methicillin resistant; Saudi Arabia; Staphylococcus aureusOnline: 22 May 2009DOI: 10.3329/bmrcb.v35i1.1983Bangladesh Med Res Counc Bull 2009; 35: 28-30

The main goal of this study was to examine the spectrum of Enterococci that cause urinary tract infection in newborns. This study was conducted during September 2018 to November 2018 at Prince Sattam Bin Abdul Aziz University. A total of 317 urine samples were taken from newborns admitted to the Children's Hospital in the city of Riyadh, Kingdom of Saudi Arabia. In total, 30 (9.5%) Enterococcal strains were isolated from 317 samples. Of these, 17 (56.6%) were from male and 13 (43.4%) were from female patients. From antibiotic sensitivity assay, it was observed that all of the isolates were resistant to clindamycin. But Imipenem and Augmentin were found highly sensitive. So, these sensitive antibiotics can be used for the treatment of newborns UTIs caused by the enterococcal strains. Dhaka Univ. J. Pharm. Sci. 19(2): 119-124, 2020 (December)