genes such as KRAS have been found in capillary malformations and result in capillary malformation overexpression of growth factors and matrix metalloproteinases. 1,3,4 As a site where gene mutations known to cause both BCC development and tissue growth upregulation are found, capillary malformations could be more predisposed to BCC development. They are in essence a locus minoris resistentiae for BCCs, with the potential for more rapid tumour growth. Minimising other BCC risk factors including UV radiation and regular capillary malformation monitoring for tumour development is therefore important in capillary malformation management, even where the capillary malformation is no longer visible.
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