This study was carried out to examine the preventive impact of marine extracts of rosemary and lemon individually or together in adult-male rats with liver injury induced by carbon tetrachloride. The extracts were prepared and tested on 40 male rats distributed into groups by collecting blood samples and conducting some hematological and biochemical parameters. CCl4-induced significant increases in the weight of the liver and heart, while rosemary and lemon extracts alone were not able to restore the liver weight, but the effect was in the synergy. As well, the extracts alone or in combination had a significant impact on reducing heart weight. Additionally, CCl4 caused a substantial reduction in RBC, Hb, PCV, MCV, MCHC and lymphocytes, whereas WBC, monocyte and granulocyte increased. While extracts exhibited an enhancement in these parameters, the best effect was when the two extracts were used together. The biochemical parameters indicated high significance in glucose, AST, ALT and triglycerides; however, total protein, albumin, cholesterol and T-AOC decreased compared to the control group. Both rosemary and lemon worked to restore and remove the oxidative effect. Keywords: Rosemary(A plant that grows in mountainous regions), Lemon, Carbon tetrachloride, Stress, Rats.
The current study deal with the effect of tramadol injections on body weight and some blood components in 40 male laboratory rats, divided into four groups. The first group, G1 represents the control group. The second group G2 and the third group G3 were injected with a concentration of 20 and 40 mg/100 g of body weight, respectively, and the fourth group G4 was injected at a concentration of 80 mg / 100 g of body weight for ten days respectively. The current study results showed a significant decrease in the weights of rats injected with tramadol compared to the control group. Also, there was a significant decrease in the numbers of RBC, PLT, MID#, and GRAN#, respectively. The concentrations of each of the following constants: HGB, HCT, MCV, MCH, and MCHC showed a significant decrease in their values; except for MCV, the decrease was not significant, and the results of this study also recorded a significant increase in the white blood cells count as well as the number of lymphocytes, and there was an increase in both RDW-CV & RDW-SD. Keywords. Body weight, tramadol, RBC, WBC, PLT.
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