ᅟWe investigated the occurrence of bleeding complications in patients who underwent skin tumor surgery and compared it between Aspirin users and a placebo control group. In this double blind randomized controlled trial, 32 patients who continued taking aspirin (intervention group) and 38 patients who stopped taking Aspirin (placebo group) before surgery were compared in terms of intraoprative and postoperative bleeding problems, hematoma and local signs of coagulopathy. There was no statistically significant difference in intraoprative bleeding between the study groups (P = 0.107). We concluded that continuation of Aspirin therapy had no significant effect on bleeding complications in patients who underwent skin tumor surgery.Trial registrationIRCT201602049768N5Graphical abstractFlow chart of the study process and its final finding

This study revealed that midfacial pattern and nasolabial crease shape are different between Persian (Iranian) and Western subjects. It seems that based on these differences and some other unknown anatomic diversity between different races, some of the defined cosmetic frames may need minor revisions to be applicable for Persian faces. More studies in this field are recommended.