In this study, soils, well waters, drinking waters, and waste water in the Isfahan industrial area were sampled in spring and summer 2018. In 8 points of industrial zone, important toxic heavy metals such as, lead (Pb), Cobalt (Co), Nickel (Ni), Chromium (Cr), and Cadmium (Cd) were sampled from surface soil (up to 2 m), well/drinking waters and waste water. After sample preparation with micro-wave digestion technique, the concentration of heavy metals was determined by electro-thermal atomic absorption spectrometry (ET-AAS). According to the well water analysis, the mean concentration of Cr, Ni, Co, Cd, and Pb in well water were 95 μg L-1, 146 μg L-1, 185 μg L-1, 12 μg L-1, and 11 μg L-1, respectively. In well water, the concentrations of Cd, Ni, Cr and Co were found much higher than Pb in comparison with the references of World Health Organization (WHO).