A baby girl presented with an antenatal diagnosis of a retroperitoneal tumour. Postnatal imaging suggested that this mass contained two fetiform structures with spine and long bone formation. This teratomatous mass was completely excised at 3 weeks of age. Histology was consistent with twin fetuses-in-fetu, revealing two fetiform masses each with an umbilical cord connecting to a common placenta-like mass. Despite a difference in the weight of the twin fetuses-in-fetu, the level of organogenesis was identical and corresponded to fetuses of 10 weeks of gestation. Each mass had four limbs, intact skin, rib cage, intestines, anus, ambiguous genitalia, primitive brain tissue and a spine with ganglion cells in the cord. Although considered a mature teratoma in the current World Health Organization classification, the theory of formation from multiple pregnancies has been commonly implied in more recent literature. The true aetiology of this rare condition remains unclear.
Undifferentiated nasopharyngeal carcinoma is particularly common in Southern China and is consistently associated with Epstein-Barr virus. In contrast, lymphoepithelioma-like carcinoma of the bile duct is a rare disease and not always associated with Epstein-Barr virus. We report the first case of coexisting Epstein-Barr virus-associated nasopharyngeal carcinoma and lymphoepithelioma-like carcinoma of the bile duct in aChinese patient. 中文摘要 兩種Epstein-Barr病毒相關惡性腫瘤並存:一名有未分化鼻咽癌病史的 病人併發淋巴上皮瘤樣膽管癌 戴燕萍、顏繼昌、丁信顯 未分化鼻咽癌在南中國地區特別常見,發病通常與Epstein-Barr病毒相關。相反,淋巴上皮瘤樣膽管 癌是一種罕見疾病,且不一定與Epstein-Barr病毒相關。本文報告首個併發Epstein-Barr病毒相關性鼻 咽癌和淋巴上皮瘤樣膽管癌的華籍病例。
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