This study’s main purpose is to provide helpful information using blood samples from COVID-19 patients as a non-medical approach for helping healthcare systems during the pandemic. Also, this paper aims to evaluate machine learning algorithms for predicting the survival or death of COVID-19 patients. We use a blood sample dataset of 306 infected patients in Wuhan, China, compiled by Tangji Hospital. The dataset consists of blood’s clinical indicators and information about whether patients are recovering or not. The used methods include K-nearest neighbor (KNN), decision tree (DT), logistic regression (LR), support vector machine (SVM), random forest (RF), stochastic gradient descent (SGD), bagging classifier (BC), and adaptive boosting (AdaBoost). We compare the performance of machine learning algorithms using statistical hypothesis testing. The results show that the most critical feature is age, and there is a high correlation between LD and CRP, and leukocytes and CRP. Furthermore, RF, SVM, DT, AdaBoost, DT, and KNN outperform other machine learning algorithms in predicting the survival or death of COVID-19 patients.
Negative binomial-based safety performance functions (SPFs) have been extensively used by United States Department of Transportation professionals for predictive crash analysis. Recently, the Florida Department of Transportation (FDOT) has developed a context classification approach and incorporated it into crash prediction models, which has the potential to significantly enhance their accuracy and reliability. The additional modeling contexts and parameters make it more challenging to diagnose and remedy modeling problems, however. Particularly for roadway segments with low annual average daily traffic (AADT), short lengths, or low counts of severe crashes, the SPF models significantly underestimate the actual number of crashes. This uncertainty in SPF predictions can lead FDOT practitioners to reach misleading conclusions, such as failing to detect sites with genuinely high crash rates. This project intends to establish thresholds for certain SPF parameters to ensure reliable crash predictions are obtained across various context classes. For this purpose, we (a) developed a functional statistical model that quantifies economic loss relative prediction errors as a function of AADT volume and (b) calculated the minimum context-specific AADT threshold for each segment length group, roadway category, context classification, and crash severity combination. Employing the developed AADT thresholds confirmed up to 89% reduction in SPF prediction errors for the most represented context class. In light of the results obtained, we are able to conclude that context-specific AADT thresholds perform well in significantly reducing prediction errors for the thresholded segments and contexts on Florida roadways.
PurposeThis paper deals with the combined management and design of a sustainable pharmaceutical supply chain network with considering recycling.Design/methodology/approachThis paper first utilizes the analytical hierarchy process to select and rank green manufacturers. Second, the authors proposed a multi-objective nonlinear mathematical model to design a sustainable pharmaceutical supply chain network. The proposed model has been linearized and solved using the LP-metric method using GAMS software.FindingsA real case study has been conducted in Iran. The results show that environmental and social issues can be improved while minimizing total costs.Originality/valueGiven the criticality and importance of drugs in human health and the importance of recycling in today's world, proper management and design of a sustainable drug supply chain are necessary. This study pays special attention to environmental issues by utilizing multi-criteria decision approaches and customer satisfaction.
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