Background. Clinical and pathologic features of oral and maxillofacial malignant lesions are very important and useful in diagnostic and therapeutic planning. The aim of this study was to determine and compare the clinicopathologic features of different types of oral and maxillofacial cancers in Cancer Registry System at Isfahan-Iran. Methods. In this cross-sectional descriptive analytic study, required data (tumor type, tumor location, age, sex, and grade of malignancy) of 1081 patients from Isfahan Cancer Registry collected. Results. In this study, the mean age of the patients was 59.9±18.5years old. Most of the patients were male (56.43%). In this study, squamous cell carcinoma was the most common malignancy (61.9%) followed by non-Hodgkin's lymphoma (7%). The most common site was tongue (38.7%) and then the nasopharynx (13%). Also nasopharynx tumors in men were more common than women (P <0.001). Conclusion. Squamous cell carcinoma, as the most common oral and maxillofacial cancer, requires considerable attention and rapid and appropriate diagnosis and treatment. Knowing the clinical and pathological features of this cancer and risk factors can improve the prognosis of patients.
Juvenile ossifying fibroma of the jaws is an aggressive variant of ossifying fibroma that tends to affect children and adolescents. Early detection and immediate treatment are essential for this condition due to its different clinical behavior, highly aggressive nature, and high tendency for recurrence. Our report describes a case of juvenile ossifying fibroma in a 27-year-old woman who presented with swelling on the left side of the face, with typical clinical, radiological, and histological features. The patient underwent surgery to remove the lesion, and after resection of the involved area, no further symptoms were reported in the follow-up sessions. CBCT scans and panoramic imaging of the patient 6 months after surgery revealed no radiographic sign of recurrence. Autologous iliac crest grafting was performed for reconstruction of the resected area.
Objectives
This study aimed to evaluate the level of adrenocorticotropic hormone (ACTH) and adrenal insufficiency in patients with mucocutaneous pemphigus lesions who use oral corticosteroids.
Methods
This descriptive-analytical study was performed on 54 patients (48.44 ± 12.74 years) with mucocutaneous pemphigus in 2019. Those patients taken corticosteroids in different doses and way. At first, collected patients information including age, sex, type of pemphigus, duration of use, patient dosage, duration of corticosteroid administration, and method of administration were collected daily. Adrenal gland function was measured by evaluating ACTH levels. Data were analyzed by using Pearson correlation coefficient and t-test.
Results
Our study showed that 37 cases (68.5%) had normal ACTH average hormone level (7.3–63.3 mL/pg), 11 cases (20.4%) were lower levels (<7.2 mL/pg), and 6 cases (11.1%) were higher levels (63.3 > mL/pg). Wo observed no significant relationship between ACTH and duration of corticosteroids usage (p=0.207).
Conclusions
Taking a maintenance dose of between 12.5 and 25 mg daily does not usually lead to adrenal insufficiency. The present study showed that the lower the daily dose of corticosteroids, the lower the likelihood of adrenal insufficiency.
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