Background Epilepsy is one of the most common neurological disorders with physical, emotional, and social consequences. Previous studies indicate that epilepsy symptoms can highly affect the epileptic patients’ satisfaction in life. The aim of the present study is to investigate the QOL of People with Epilepsy (PWE) in Khorasan Razavi province, Iran. Methods In this study, 100 patients were randomly selected. After confirmation of the diagnosis of epilepsy by neurologists and fulfilling the entrance criteria, patients completed the Quality of Life in Epilepsy-31 inventory (QOLIE-31) questionnaire. Finally, data was analyzed statistically by SPSS software. Results The study sample comprised 100 PWE, aged 18–74 years (34 ± 13), of whom 58 (58%) were females. Tonic-colonic seizure was the most common (60%) type of seizure. The obtained score of each subscale and the range of the QOLIE-31 total score was 16.40–79.18 with the mean of 50 (SD = 16). The energy-fatigue subscale score was significantly higher in patients younger than 35 (p = 0.018). The data analysis showed that the seizure worry subscale was significantly higher in single patients (p = 0.04). Duration of epilepsy had a positive correlation with QOLIE-31 total score (p = 0.038), and a negative relationship with energy-fatigue subscale (p = 0.018). In contrast with previous studies, which reported the frequency of the epileptic episodes as the most important predictor of QOL, our results showed no significant correlation between the number of the episodes and overall QOL score (p = 0.063). However, the number of episodes was significantly correlated with emotional well-being and cognition subscales. Furthermore, the results indicated that poor QOL score is correlated with depressed mood. Conclusion In fact, the ultimate and preferred outcome of all treatments and care interventions is the patient’s QOL. Thus, improvement of the QOL by means of obtaining more information about its contributing factors, in PWE should be one of the main goals in the patients’ treatment.
Objective:To investigate the demographic and clinical characteristics of epilepsy in 2 referral hospitals in northern Iran.Methods:In this cross-sectional study, we evaluated 300 patients with the confirmed diagnosis of epilepsy referred to the Neurology clinics of 22-Bahman, and 17-Shahrivar Hospitals, Mashad, Iran, from April 2011 to December 2012. We collected and analyzed demographic and disease information.Results:The mean age of patients was 31.5 ± 15.3 years. The diagnosis of disease had been made approximately 10 months after the onset of symptoms, and the treatment gap was 28%. The most widely used anticonvulsants were sodium valproate, carbamazepine, and phenobarbital. Generalized seizure was seen in 78%, partial seizure in 22%, and a combination of them in 11% of patients. Tonic-colonic seizure (72%) was the most common type of generalized epilepsy, and secondarily generalized seizure was the most frequent type of partial epilepsy.Conclusion:The epidemiological features of epilepsy in our region with regard to age and gender are the same as other parts of the world. The generalized type is the most common form of epilepsy, with tonic-colonic seizures being the most frequent type in our area.
Materials and Methods:In this analytical cross-sectional study, 120 patients with PD were selected from 22-Bahman and 17-Shahrivar hospitals. Demographic information was recorded on a form and Parkinson's severity was determined using the Hoehn and Yahr scale (HY). Pittsburgh Sleep Quality Index (PSQI) and Epworth sleepiness scale (ESS) were used for the assessment of sleep quality and excessive daytime sleepiness, respectively. Cognitive status was assessed using the Montreal Cognitive Assessment questionnaire. Results:The mean age of patients with PD was 65.9±11.7 years, and 67.5% were men. Cognitive impairment was found in 113 (94.2%) patients, poor sleep quality in 87 (72.5%), and excessive daytime sleepiness in 27 (22.5%) patients. The mean PSQI and ESS scores were 9.03±4.70 and 7.38±3.73, respectively. There was a significant association between cognitive status and sleep quality, as well as daytime sleepiness (independent sample t-test, p<0.0001 for both). Conclusion:There is a significant association between cognitive impairment and poor sleep quality as well as excessive daytime sleepiness. Bulgular: PH hastalarının yaş ortalaması 65,9±11,7 yıl idi ve bunların %67,5'i erkekti. Hastaların 27'sinde (%22,5) kognitif bozukluk, 87'sinde (%72,5) gündüz aşırı uykululuk ve 113'ünde (%94,2) kötü uyku kalitesi bulundu. PUKİ ortalama ve ESS skorları sırasıyla 9,03±4,70 ve 3,73±7,38 idi. Kognitif durum ve uyku kalitesi yanı sıra gündüz uykululuk arasında bir anlamlı ilişki saptandı (p<0,0001). Sonuç:Kognitif bozukluk ve kötü uyku kalitesi yanı sıra gündüz aşırı uykululuk arasında anlamlı bir ilişki vardır.
Background: Although much research on patients with epilepsy (PWE) has focused on psychiatric disorders such as depression, anxiety, and psychotic disorders, the relationship between epilepsy and personality disorders has not been frequently studied. Objectives: The study aimed to evaluate borderline personality traits in PWE. Materials & Methods: In this case-control study, we evaluated 211 PWE who were consecutively referred to 22 Bahman Hospital, Mashhad, Iran, in 2021. We also compared the patients with an age-matched and gender-matched control group. The Borderline personality traits were assessed by the second subscale of the schizotypal questionnaire (STB) which is known as the borderline personality scale questionnaire. Data were coded and analyzed by SPSS software, version 20. Results: Epilepsy group had significantly higher borderline personality features in comparison with the control group (P=0.029). PWE had significantly higher scores in hopelessness (P=0.017) and impulsivity factors (P=0.046) on the STB questionnaire. Our results revealed that PWE who were married (P=0.011) and who had epilepsy for more than 10 years, had significantly higher borderline personality traits (P=0.04). Conclusion: PWE are more likely to have borderline personality traits. Therefore, it is important to screen epileptic patients to detect it earlier to avoid further consequences and its possible effects on therapeutic responses.
Objectives: This study aimed to evaluate some speech disorders in groups of patients with Lewy body spectrum disorders (LBSD), compare the groups in order to identify the possible causes of the disorders, and improve the given patients’ quality of life by helping them manage the development of speech disorders and rehabilitation of them. Methods: The present case-control study was performed to examine a total of 40 individuals, including 10 healthy people as controls and 30 patients with a range of LBSD diagnosed based on the criteria for cognitive neurological and motor disorders published by the University of Pennsylvania Department of Neurology. Results: The four groups were similar in age and sex distribution and were not statistically and significantly different. The highest score of short mental state test (MMSE) was obtained for the control group. Parkinson’s patients with dementia spent the longest time to tell the story. The highest number of sentences was also produced by the Parkinson’s disease (PD) group. The control group faced the least number of vocabulary retrieval problems when narrating the story. On the other hand, the most frequent word retrieval problem was observed in dementia with Lewy bodies, followed by Parkinson’s disease with dementia (PDD). There was a significant difference between the control group with dementia and the Lewy body in terms of frequency distribution of action and search theme. There were also significant differences among four groups regarding the global and local connectedness of storytelling as well as the number of keywords used. Conclusions: In sum, a considerable speech disorder was observed in patients with LBSD, which was more evident in two groups with dementia. Therefore, dementia may have been the main cause of these impairments.
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