most common identified mutations are factor V Leiden (FV Leiden), prothrombin 20210G>A (FII G20210A), methylenetetrahydrofolate reductase 677 C>T (MTHFR C677T), and 1298A>C (MTHFR A1298C) (3-5). FV Leiden and FV Hong Kong mutations of FV gene can render FVa resistant to activated protein C because of a loss of 306 and 506 cleavage sites, respectively (6). FV Leiden predisposes the patient to thrombosis 7 ; however, the FV Hong Kong mutation is a substitution of A>G in the 1090th nucleotide of factor V gene (6) and is still a matter of contention. The transition at nucleotide position 20210 in 3 untranslated region of the factor II gene is associated with elevated Inherited disorders related to hemostatic system are known as risk factors for thromboembolic events such as myocardial infarction, stroke, pulmonary embolism, pregnancy complications, and especially recurrent deep vein thrombosis (DVT) (1,2). The