Constraint satisfaction problems are a central pillar of modern computational complexity theory. This survey provides an introduction to the rapidly growing field of Quantum Hamiltonian Complexity, which includes the study of quantum constraint satisfaction problems. Over the past decade and a half, this field has witnessed fundamental breakthroughs, ranging from the establishment of a "Quantum Cook-Levin Theorem" to deep insights into the structure of 1D low-temperature quantum systems via so-called area laws. Our aim here is to provide a computer science-oriented introduction to the subject in order to help bridge the language barrier between computer scientists and physicists in the field. As such, we include the following in this survey: (1) The motivations and history of the field, (2) a glossary of condensed matter physics terms explained in computer-science friendly language, (3) overviews of central ideas from condensed matter physics, such as indistinguishable particles, mean field theory, tensor networks, and area laws, and (4) brief expositions of selected computer science-based results in the area. For example, as part of the latter, we provide a novel information theoretic presentation of Bravyi's polynomial time algorithm for Quantum 2-SAT.Comment: v4: published version, 127 pages, introduction expanded to include brief introduction to quantum information, brief list of some recent developments added, minor changes throughou

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Information technologies enable programmers and engineers to design and synthesize systems of startling complexity that nonetheless behave as intended. This mastery of complexity is made possible by a hierarchy of formal abstractions that span from high-level programming languages down to low-level implementation specifications, with rigorous connections between the levels. DNA nanotechnology presents us with a new molecular information technology whose potential has not yet been fully unlocked in this way. Developing an effective hierarchy of abstractions may be critical for increasing the complexity of programmable DNA systems. Here, we build on prior practice to provide a new formalization of ‘domain-level’ representations of DNA strand displacement systems that has a natural connection to nucleic acid biophysics while still being suitable for formal analysis. Enumeration of unimolecular and bimolecular reactions provides a semantics for programmable molecular interactions, with kinetics given by an approximate biophysical model. Reaction condensation provides a tractable simplification of the detailed reactions that respects overall kinetic properties. The applicability and accuracy of the model is evaluated across a wide range of engineered DNA strand displacement systems. Thus, our work can serve as an interface between lower-level DNA models that operate at the nucleotide sequence level, and high-level chemical reaction network models that operate at the level of interactions between abstract species.

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