Our data further support the importance of EGFR mutation with regard to gefitinib sensitivity. In addition to its predictive role, EGFR mutation confers significant survival benefits on NSCLC patients treated with gefitinib.
A remediation technique involving surfactant foam (SF)
was investigated by using a micromodel with a view toward
improved contaminant displacement. A residual trichloroethylene (TCE) saturation was emplaced in an otherwise
water-saturated micromodel. Air flow was introduced to
a surfactant solution flow (Sodium C14
-
16 olefin sulfonate 2%(w)) commonly utilized in surfactant flushing to obtain
the SF. Conventional remediation strategies, surfactant
flushing, water flooding, and gas flooding were also employed
for comparison to the SF flooding. The removal efficiency
was quantified by directly measuring the remaining TCE
blob area with an image analyzer. The micromodel visualization
showed that the SF is capable of displacing a higher
amount of TCE as compared to surfactant solution alone.
The SF flooding removed 99% of the residual TCE,
while surfactant flushing removed 41% with 25 pore
volumes of the same surfactant solution. Based on micromodel
visualization, the resulting enhanced removal of TCE
blobs due to direct and indirect displacements, increased
solubility and blob snap-off were investigated. The
micromodel was also oriented vertically, and no vertical
movement of the TCE was observed during SF flooding. Thus,
the SF flooding achieved high TCE removal efficiency
without lowering the interfacial tension to an ultralow value
and causing vertical migration, which has been of
particular concern in TCE removal.
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