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A simple design, which we believe to be the first of its kind, of an all-fiber-based optical source is proposed for the generation of widely tunable few-cycle pulses as short as 20-25 fs duration in the range of 1.6-2.1 microm. Few-cycle pulses are obtained by compression of femtosecond pulses from the erbium-doped fiber laser in a three-stage scheme that uses (i) the effects of the soliton compression and the Raman frequency tuning in the dispersion decreasing fiber, as well as (ii) supercontinuum generation in a high-nonlinear silica fiber, and (iii) subsequent compression in a short conventional fiber.

We demonstrate that optical coherence tomography (OCT) is a convenient diagnostic tool to monitor pulse-to-pulse kinetics in laser interactions with biological tissue. In experiments on laser modification and ablation of the cataractous human lens and the porcine cornea we have applied this technique in situ to investigate different modes of preablation tissue swelling, crater formation and thermally affected zone development. The cataractous lens is an example of highly scattering media whereas the cornea is initially low scattering. The radiation with different wavelengths has been employed including that of a YAG:Er laser (λ=2.94 μm), a glass:Er laser (λ=1.54 μm), YAG:Nd lasers (λ=1.32 μm and λ=1.44 μm), as well as of the fifth harmonic of a Nd:YAP laser (λ=0.216 μm). Pulse-to-pulse OCT monitoring has been accompanied by the probe beam shielding diagnostics to provide the time-resolved observation of the interaction dynamics. © 1999 Society of Photo-Optical Instrumentation Engineers.

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