A historical perspective on the issue of device-based endometrial destruction is presented. The article describes in detail various current methods of thermal coagulation of the uterine mucosa for its destruction. A comparative analysis of hysteroscopic and non-hysteroscopic methods of endometrial destruction in terms of treatment effectiveness, complications, and recurrence prevention is presented. The ways of technological development of instrumental treatment methods of intrauterine disorders are highlighted.
The article presents data on the management of pregnancy in women with eye diseases. Ophthalmological manifestations in various pathological conditions on the part of the organs of vision are clearly shown. Presents the procedure for management of pregnancy and childbirth in women with both eye diseases and ophthalmic morpho-functional changes associated with the development of gestational complications. The admissibility of carrying out laser-surgical treatment methods for pathological changes in the organs of vision in a pregnant woman is noted. Ophthalmological changes are indicated, which are taken into account when choosing a mode of delivery.
Huge resources of the health system and economies of all countries of the world are devoted to combating the COVID-19 pandemic (Coronavirus disease 2019). It is important to formulate effective measures to prevent the spread of a new coronavirus infection and the development of its postcoid complications. For this, it is necessary to study in depth not only the etiopathogenesis, clinical manifestations of the disease, but also to assess the influence of another pathology on the course of the development of the disease. Particular attention should be paid to pregnant patients with COVID-19. To clarify the relationship between COVID-19 and iron deficiency anemia. The information material includes data from scientific articles available in Pubmed and Internet resources on this topic, as well as data from our own observations. Timely diagnosis and treatment of iron deficiency anemia in pregnant women helps not only to prevent the development of obstetric and perinatal complications, but also to prevent the development of a severe course of COVID-19.
Background. The high contagiousness and susceptibility of a pregnant woman's body to a new coronavirus infection requires study not only of etiopathogenesis, but also of developing methods to prevent the development of this disease.
Aim. To evaluate the preventive effectiveness of the use of a drug containing recombinant interferon alfa-2b (IFN-a2b) and an antioxidant complex in pregnant women during their stay in the family focus of a new coronavirus infection.
Materials and methods. 75 pregnant women were under observation, in whose family there were patients infected with the virus that causes a new coronavirus infection. Treatment of sick relatives was carried out at home, as the disease in them proceeded in an uncomplicated form. The main group was formed by 37 pregnant women who treated the nasal mucosa with a preparation containing recombinant IFN-a2b in the amount of 5000 IU and an antioxidant complex (alpha-tocopherol acetate, citric and benzoic acids). The comparison group was formed by 38 pregnant women who did not use any drugs for prophylactic purposes. All patients observed generally accepted rules of personal hygiene and behavior. The duration of prophylactic use of the indicated medicinal product depended on obtaining a negative result for the causative agent of a new coronavirus disease, an infected family member. A smear from the nasopharynx and oropharynx was examined to detect SARS-CoV-2 RNA by PCR once every 57 days.
Results. COVID-19 vaccination did not exclude infection with the SARS-CoV-2. Preventive treatment of the nasal mucosa with an IFN-a2b containing drug reduced the risk of infection with this viral agent in vaccinated patients who were in household contact with a patient with COVID-19 by 6 times. Asymptomatic and mild course of a new coronavirus infection was observed in 3 (25%) and 7 (58.3%) patients of 12 infected women from the main group and in 8 (22.9%) and 18 (51.4%) patients of 35 infected women from the comparison group, respectively. Further local use of the drug containing recombinant IFN-a2b and an antioxidant complex contributed to a decrease in the duration of infection and the course of the disease. Progression of COVID-19 was observed in unvaccinated patients with concomitant somatic pathology (diabetes mellitus, iron deficiency anemia, cardiovascular diseases, etc.): 2 (16.7%) and 9 (25.7%) people in groups, respectively.
Conclusion. The use of recombinant IFN-a2b with an antioxidant complex in pregnant women with a family focus of new coronavirus infection is clinically appropriate and highly effective.
There are presented own data on the prevalence of uterine fibroids in women in different age groups, as well as with infertility, miscarriage and other diseases of the internal genital organs. An unusual case of a combination of the uterine form of pregnancy associated with a large submucous myoma node is considered. The use of new original technologies was shown to contributes to the reduction of blood loss during simultaneously performing surgical delivery and myomectomy.
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