Prevention of postoperative pain in children is one of the most important objectives of the anesthesiologist. Opioids have been used as an analgesic for postoperative pain in children for many years. Tramadol has both opioid and monoaminergic agonist actions. The aim of the study was to determine if the analgesic potency and occurrence of adverse effects of tramadol differ from pethidine when administered to children. A total of 110 healthy children, aged 2-12 years, scheduled for elective lower abdominal surgery were randomized to receive either pethidine 1 mg/kg (Group I, n = 60) or tramadol 2 mg/kg (Group II, n = 50) for postoperative pain after anesthesia induction. Pain intensity, adverse effects, heart rate, and systolic and diastolic blood pressure were recorded at regular intervals. The mean pain scores on postoperative 24 h were significantly greater with tramadol than with pethidine. Sedation scores, heart rate and systolic and diastolic blood pressure showed no significant differences between the groups. We conclude that pethidine and tramadol are effective in providing analgesia in pediatric patients, but pethidine provided better postoperative analgesia than tramadol. Changes in blood pressure, heart rate and arterial oxygen saturation were minimal and were similar in both drugs.
ÖZ Yüksek mortalite ve morbidite nedeniyle mantar zehirlenmesi karaciğerde ve böbreklerde hasara neden olan önemli bir acil durumdur, ancak kardiyak fonksiyonlara olan etkisi henüz belirlenmemiştir.Kardiyotoksisite,hepatik toksisite,nefrotoksisite ile komplike olmuş 44 yaşında bir kadın mantar zehirlenmesi olgusunu sunmayı amaçladık.Mantar zehirlenmesi olan hastalar klinik belirtiler,elektrokardiyografi,ekokardiyografi,kardiyak enzimlerle kardiyak zehirlenme açısından da değerlendirilmelidir. Anahtar Kelimeler: Mantar zehirlenmesi, kardiyotoksisite, amatoksin ABSTRACT Because of the high mortality and morbidity, mushroom poisoning is a significant medical emergency that causes liver and kidney damage; however, its effect on cardiac functions has not been established yet. We aimed to present a 44-year-old woman who was poisoned by mushroom and complicated with hepatic, renal and cardiac toxicity. Patients who had mushroom poisoning should also be evaluated especially in terms of cardiac dysfunction with clinic signs, electrocardiography, cardiac enzyme tests and echocardiography.
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