We propose a microwave signal generation system for brain stimulation. The existing brain stimulation system uses a signal of several tens of kHz, and the magnetic field distribution is wide. Microwave is used to locally limit the distribution of the electromagnetic field and to change the action potential of the cell with less power. The switch modulates the microwave signal to obtain a pulse envelope. The action potential of the cell can be controlled to the excitation/inhibition state by adjusting the repetition frequency. These results are confirmed by measuring the cell potential of the mouse brain. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ⓒ

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