Optimal virtual monochromatic imaging using Mono+ algorithm demonstrated better image quality for gray-white matter differentiation and reduction of the artifact in the posterior fossa.

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Objective To compare the radiation dose and the objective and subjective image quality of 80 kVp and 80/150 kVp with tin filter (80/Sn150 kVp) computed tomography (CT) in oncology patients. Methods One-hundred-and-forty-five consecutive oncology patients who underwent third-generation dual-source dual-energy CT of the abdomen for evaluation of malignant visceral, peritoneal, extraperitoneal, and bone tumor were retrospectively recruited. Two radiologists independently reviewed each observation in 80 kVp CT and 80/Sn150 kVp CT. Modified line-density profile of the tumor and contrast-to-noise ratio (CNR) were measured. Diagnostic confidence, lesion conspicuity, and subjective image quality were calculated and compared between image sets. The effective dose and size-specific dose estimate (SSDE) were calculated in the image sets. Results Modified line-density profile analysis revealed higher attenuation differences between the tumor and normal tissue in 80 kVp CT than in 80/Sn150 kVp CT (127 vs. 107, P = 0.05). The 80 kVp CT showed increased CNR in the liver (8.0 vs. 7.6) and the aorta (18.9 vs. 16.3) than the 80/Sn150 kVp CT. The 80 kVp CT yielded higher enhancement of organs (4.9 ± 0.2 vs. 4.7 ± 0.4, P<0.001) and lesion conspicuity (4.9 ± 0.3 vs. 4.8 ± 0.5, P = 0.035) than the 80/ Sn150 kVp CT; overall image quality and confidence index were comparable. The effective dose was reduced by 45.2% with 80 kVp CT (2.3 mSv ± 0.9) compared to 80/Sn150 kVp CT

ObjectiveTo compare quantitative and qualitative image quality parameters in pediatric abdominopelvic dual-energy CT (DECT) using noise-optimized virtual monoenergetic image (VMI) and conventional VMI at different kiloelectron volt (keV) levels.Materials and MethodsThirty-six consecutive abdominopelvic DECT scans were retrospectively included. Noise-optimized VMI and conventional VMI were reconstructed at seven energy levels, from 40 keV to 100 keV at 10 keV intervals. The contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) of the liver, pancreas, and aorta were objectively measured and compared. Image quality was evaluated subjectively regarding image noise, image blurring of solid organ, bowel image quality and severity of beam-hardening artifacts. Optimal monoenergetic levels in keV for both algorithms were determined based on overall image quality score.ResultsThe maximal CNR and SNR values for all investigated organs were observed at 40 keV in noise-optimized VMI (CNR and SNR of liver, pancreas, aorta in order [CNR; 20.93, 17.34, 46.75: SNR; 37.39, 33.80, 63.21]), at 60–70 keV and at 70 keV in conventional VMI (CNR; 8.12, 5.67, 15.97: SNR; 19.57, 16.66, 26.65). In qualitative image analysis, noise-optimized VMI and conventional VMI showed the best overall image quality scores at 60 keV and at 70 keV, respectively. Noise-optimized VMI at 60 keV showed superior CNRs, SNRs, and overall image quality scores compared to conventional VMI at 70 keV (p < 0.001).ConclusionOptimal energy levels for noise-optimized VMI and conventional VMI were 60 keV and at 70 keV, respectively. Noise-optimized VMI shows superior CNRs, SNRs and subjective image quality over conventional VMI, at the optimal energy level.

Background With the increasing number of computed tomography (CT) scans used for evaluation of acute abdominal pain, patient radiation exposure has increased rapidly. Purpose To determine whether the diagnostic performance of half-dose abdominopelvic CT is non-inferior to that of standard-dose CT for patients with acute abdominal pain. Material and Methods Ninety-eight patients with acute abdominal pain underwent dual-source abdominopelvic CT. Three sets of CT images were reconstructed: standard-dose filtered back projection (FBP); half-dose FBP; and half-dose sinogram-affirmed iterative reconstruction (SAFIRE3). Diagnostic performance of the standard-dose scan was compared with that of the half-dose scans by using a non-inferiority test with a 10% margin. The overall image quality was subjectively measured. Results Diagnostic performance for overall disease diagnosis with half-dose scans (area under the receiver operating characteristic curve [AUC] = 0.835 for FBP, 0.881 for SAFIRE3) was non-inferior to that of standard-dose FBP (AUC = 0.891) (95% confidence interval lower limit difference = −5.6% [half-dose FBP], −1.2% [half-dose SAFIRE3]). The diagnostic sensitivity for detection of neoplastic disease was lower with half-dose (75.0%) than with standard-dose FBP (91.7%). Effective dose and dose-length product with standard-dose imaging were 7.99 ± 2.55 mSv and 533.1 ± 170.3 mGy·cm, respectively; those of half-dose imaging were 3.99 ± 1.28 mSv and 266.6 ± 85.2 mGy·cm, respectively. The image quality was lower with half-dose than with standard-dose FBP scans (P < 0.01). Conclusion Diagnostic performance of half-dose CT is non-inferior to that of standard-dose scan for evaluation of acute abdominal pain, despite inferior image quality.