Adiponectin plays important roles in metabolic function, inflammation and multiple biological activities in various tissues. However, evidence for adiponectin signaling in sebaceous glands is lacking, and its role remains to be clarified. This study investigated the role of adiponectin in lipid production in sebaceous glands in an experimental study of human sebocytes. We demonstrated that human sebaceous glands in vivo and sebocytes in vitro express adiponectin receptor and that adiponectin increased cell proliferation. Moreover, based on a lipogenesis study using Oil Red O, Nile red staining and thin layer chromatography, adiponectin strongly upregulated lipid production in sebocytes. In three-dimensional culture of sebocytes, lipid synthesis was markedly enhanced in sebocytes treated with adiponectin. This study suggested that adiponectin plays a significant role in human sebaceous gland biology. Adiponectin signaling is a promising target in the clinical management of barrier disorders in which sebum production is decreased, such as in atopic dermatitis and aged skin.

The following sentence is missing from the end of the Cell culture section of the Methods: 'Immortalized human SZ95 sebocytes showing morphologic and functional characteristics of normal human sebocytes were maintained and used in the experiments performed as previously described (Zouboulis et al, 1999). The reference is: Zouboulis CC, Seltmann H, Neitzel H, Orfanos CE. Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95).

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Cutaneous metastases from gastric adenocarcinoma are extremely rare. When present, metastasis typically signifies disseminated disease with a poor prognosis. We report a case of an 80-year-old male with gastric cancer who presented with a single, erythematous plaque on the left palm, a very rare site for skin metastasis. Results of a skin biopsy demonstrated that the cutaneous metastasis originated from the stomach. This report emphasized the need for appropriate investigation into newly appearing, unusual, or persistent skin lesions.

Ocular albinism (OA) is an inherited disorder characterized by partial or complete absence of pigment in the eyes. Ocular albinism is inherited in two patterns, X‐linked and autosomal pattern. X‐linked OA includes type I OA (Nettership‐Falls type), type II OA (Forsius‐Eriksson type), and OA with late‐onset sensorineural deafness. The other includes type III OA (autosomal recessive OA) and OA with sensorineural deafness.1 Among the subtypes of ocular albinism, OA with sensorineural deafness has characteristic clinical features: blue eyes, multiple lentigines, and congenital sensorineural deafness.2 This type of ocular albinism is an inherited autosomal dominant trait2 and is considered to be very rare. We report a 28‐year‐old female who was diagnosed with OA with sensorineural deafness.