Metastatic Gastric Adenocarcinoma Presenting as a Solitary Plaque on the Palm

Abstract

Cutaneous metastases from gastric adenocarcinoma are extremely rare. When present, metastasis typically signifies disseminated disease with a poor prognosis. We report a case of an 80-year-old male with gastric cancer who presented with a single, erythematous plaque on the left palm, a very rare site for skin metastasis. Results of a skin biopsy demonstrated that the cutaneous metastasis originated from the stomach. This report emphasized the need for appropriate investigation into newly appearing, unusual, or persistent skin lesions.

Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report

“…Skin metastases frequently affect the head, neck, breast, and abdominal wall. Skin metastases in gastric cancer are generally multiple nodules and sometimes cellulites or erysipelas-like lesions [ 5 , 7 , 13 – 15 ]. For the diagnosis of skin metastasis, histopathological features of biopsies conducted on lesions are important and generally show similarity with primary tumor [ 7 ].…”

“…Skin metastases in gastric cancer are generally multiple nodules and sometimes cellulites or erysipelas-like lesions [ 5 , 7 , 13 – 15 ]. For the diagnosis of skin metastasis, histopathological features of biopsies conducted on lesions are important and generally show similarity with primary tumor [ 7 ]. Determination of skin metastasis in gastric cancer is associated with poor prognosis, similar to BM metastasis, and the mean survival after diagnosis is 11.4 weeks [ 7 ].…”

“…For the diagnosis of skin metastasis, histopathological features of biopsies conducted on lesions are important and generally show similarity with primary tumor [ 7 ]. Determination of skin metastasis in gastric cancer is associated with poor prognosis, similar to BM metastasis, and the mean survival after diagnosis is 11.4 weeks [ 7 ]. Although palliative chemotherapy and radiotherapy have been applied in many patients with skin metastasis, unsuccessful results have been achieved [ 7 ].…”

“…Determination of skin metastasis in gastric cancer is associated with poor prognosis, similar to BM metastasis, and the mean survival after diagnosis is 11.4 weeks [ 7 ]. Although palliative chemotherapy and radiotherapy have been applied in many patients with skin metastasis, unsuccessful results have been achieved [ 7 ]. In our case, bone marrow and skin metastases were present.…”