Tamoxifen is a synthetic non-steroid anti-estrogen that has been used effectively for several years in the adjuvant treatment of breast cancer. But, the drug has been associated with development of endometrial poylp, hyperplasia and adenocarcinoma possibly mediated through its agonistic estrogen properties during the menopausal period in which estrogens are at a low level. Endometrial polyp has been described as the most common endometrial pathology in association with postmenopausal tamoxifen treatment. We present the case of woman with a giant endometrial polyp of uncommon dimension who was receiving adjuvant tamoxifen for 5 years after breast cancer surgery.
Objective To evaluate the clinicopathologic features of extrapelvic endometriosis in order to help diagnosis and treatment. Methods Thirty patients with extrapelvic endometriosis were surgically diagnosed at Pusan National University Hospital from January 1998 to December 2010. We retrospectively reviewed the medical records such as age, symptoms, preoperative diagnosis, past surgical history. Results There were 30 patients who were diagnosed extrapelvic endometriosis surgically with a mean age of 38 years. The main symptom was palpable mass with pain, noncyclic (33%, n=9), or cyclic (67%, n=21). Fifteen endometriomas were found in the previous scar of cesarean section and laparoscopic surgery. Three endometriomas were noted in episiotomy site and ten were in cervix. Inguinal and vaginal endometriosis, one case was investigated, respectively. Conclusion Diagnosis of extrapelvic endometriosis is diffi cult to diagnose because of its rarity and diversity of symptoms. Thus, It must be kept in mind as one of the differential diagnosis to treat patients with pain or palpable mass during menstrual cycle in or around surgical scars, even if vaginal spotting or abnormal pap test. Radical local excision help to treat and prevent recurrence of extrapelvic endometriosis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.