No abstract

The study of T and B cells subsets showed a significant higher CD4 and CD19 levels in G2 at m2. NK cells count was significant lower in the same group at m3. There were no significant differences in the levels of immunoglobulin between groups. Conclusion: This study demonstrates that laparoscopic surgery appears to be associated with similar immune responses compared with open surgery, considering that immune parameters vary slightly between groups. Although higher CRP levels showed a high level of injury in the open surgery group, the management of perioperative care through an ERAS protocol seemed to minimise the effect of open surgery associated to more postoperative complications. Further studies are be required in order to clarify the significance of the different levels of CD4, CD19 and CD56 found among groups. Disclosure of interest: None declared.