The genus Legionella is a fastidious Gram-negative bacteria widely distributed in natural waters and man made water supply systems. Legionella pneumophila is the aetiological agent of approximately 90% of reported Legionellosis cases, and serogroup 1 is the most frequent cause of infections. Legionnaires' disease is often associated with travel and continues to be a public health concern at present. The correct water management quality practices and rapid methods for analyzing Legionella species in environmental water is a key point for the prevention of Legionnaires' disease outbreaks. This study aimed to evaluate the positivity rates and serotyping of Legionella species from water samples in the region of Antalya, Turkey, which is an important tourism center. During January-December 2010, a total of 1403 samples of water that were collected from various hotels (n = 56) located in Antalya were investigated for Legionella pneumophila. All samples were screened for L. pneumophila by culture method according to "ISO 11731-2" criteria. The culture positive Legionella strains were serologically identified by latex agglutination test. A total of 142 Legionella pneumophila isolates were recovered from 21 (37.5%) of 56 hotels. The total frequency of L. pneumophila isolation from water samples was found as 10.1%. Serological typing of 142 Legionella isolates by latex agglutination test revealed that strains belonging to L. pneumophila serogroups 2-14 predominated in the examined samples (85%), while strains of L. pneumophila serogroup 1 were less numerous (15%). According to our knowledge, our study with the greatest number of water samples from Turkey demonstrates that L. pneumophila serogroups 2-14 is the most common isolate. Rapid isolation of L. pneumophila from environmental water samples is essential for the investigation of travel related outbreaks and the possible resources. Further studies are needed to have epidemiological data and to determine the types of L. pneumophila isolates from Turkey.
Amaç: Hepatit B virüsü tüm dünyada önemli bir morbidite ve mortalite nedenidir. Son yıllardaki çalışmalarda kronik hepatit B'li hastalarda rutin hematolojik parametrelerden olan ortalama trombosit hacmi (MPV) ve eritrosit dağılım genişliği (RDW) seviyeleri sağlıklı kişilere göre anlamlı olarak yüksek bulunmuştur. Bu çalışmada Hepatit B yüzey antijeni (HBsAg) pozitif olgularda MPV, RDW ve RDW/Trombosit (PLT) eritrosit dağılım genişliği/trombosit oranı (RPR) ilişkisinin araştırılması amaçlanmıştır. Yöntem: 2011-2012 yılları arasında Antalya Halk Sağlığı Laboratuvarı'na başvuran hastalar retrospektif olarak incelemeye alındı. HBsAg pozitif olarak saptanan ve yaşları 17-82 arasında değişen 349'u kadın ve 213'ü erkek olmak üzere toplam 562 hasta çalışmaya alındı. Aynı dönemde yaklaşık 3:1 hasta/kontrol oranında sağlıklı kişilerin yaş ve cinsiyet ile eşleşen kontrol grubu oluşturuldu. Kontrol grubu, yaşları 18-76 arasında değişen 121 kadın ve 80 erkekten oluşturuldu. Hastaların eş zamanlı olarak alanin aminotransferaz (ALT), aspartat aminotransferaz (AST), PLT, MPV, RDW ve RPR düzeyleri incelendi.
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