Although the Coronavirus Disease 2019 (COVID-19) infection mainly affects the lung, its gastrointestinal (GI) involvements are also well-known, especially hepatic involvement presenting as mild to moderate transaminitis. However, COVID-19 infection presenting with gall bladder involvement with acalculous cholecystitis is extremely rare in the medical literature. So far, only two cases have been reported, and herein, we are reporting the third case of a patient who developed COVID-19 presenting as an acute acalculous cholecystitis.
Antibiotic cement-coated intramedullary nails (ACCINs) are increasing in popularity as a viable solution for the treatment of fracture-related infections (FRIs), infected long bone nonunions, and arthrodeses without an external fixator. ACCINs effectively manage to fulfill three of the basic principles for eradicating osteomyelitis: dead space management, antibiotic delivery, and bone stability. We performed a retrospective review of 111 patients who were treated with ACCINs between January 2014 and December 2020. In our series, 87.4% (n = 97) of patients achieved healed and uninfected bone or stable arthrodesis at a mean follow-up of 29.2 months (range, 6–93 months). Additionally, 69.1% (n = 67) of healed patients were resolved after only one procedure, and the remainder (30.9%, n = 30) healed after one or more additional procedures. The mean number of additional procedures was 2.1 (range, 1–6 additional procedures). The overall limb salvage rate was 93.7% (n = 104). The majority of the total cohort were successfully treated in only one surgery. This study suggests that ACCINs are effective in the treatment of FRIs, infected long bone nonunions, and infected ankle and knee arthrodeses.
Hyponatremia is a recognized but underreported complication of the peripartum period. However, maternal hyponatremia in the peripartum period is a very rare cause of seizure. In this case, we highlight hyponatremia as a cause of seizures during the peripartum period.
39y old HIV positive female with isolated manifestations of pulmonary Mycobacterium Avium Complex infection being initial presentation.Pulmonary MAC infection is extremely rare, with an incidence of 1 case per 100,000 per year. we have not found any cases of newly diagnosed HIV/AIDS patients with pulmonary MAC being the initial symptom
Key Clinical MessagePulmonary MAC infection in a patient without structural lung disease is extremely rare. There is no case report of HIV/AIDS patient in known their initially presenting primary diagnosis is pulmonary MAC infection.
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